CAS 82219-78-1

Cefuzonam

Description:

Cefuzonam, with the CAS number 82219-78-1, is a synthetic antibiotic belonging to the cephalosporin class of beta-lactam antibiotics. It is characterized by its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it useful in treating various bacterial infections. Cefuzonam exhibits stability against certain beta-lactamases, enzymes produced by bacteria that can inactivate many antibiotics. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death. The compound is typically administered via injection and is often used in clinical settings for serious infections, particularly in patients who may be resistant to other antibiotics. As with other cephalosporins, it may cause allergic reactions in individuals with a history of penicillin allergies. Pharmacokinetics of cefuzonam includes absorption, distribution, metabolism, and excretion, which are essential for determining dosing regimens. Overall, cefuzonam represents an important tool in the antibiotic arsenal, particularly in the face of rising antibiotic resistance.

Formula: C₁₆H₁₅N₇O₅S₄

InChI: InChI=1S/C16H15N7O5S4/c1-28-21-9(7-5-31-16(17)19-7)12(24)20-10-13(25)23-11(15(26)27)6(4-30-14(10)23)3-29-8-2-18-22-32-8/h2,5,10,14H,3-4H2,1H3,(H2,17,19)(H,20,24)(H,26,27)/b21-9-/t10-,14-/m1/s1

InChI key: InChIKey=CXHKZHZLDMQGFF-ZSDSSEDPSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC4=CN=NS4)[H]

Synonyms:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-3-[(1,2,3-thiadiazol-5-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7S)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 1,2,3-Thiadiazole, 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid deriv.
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-, (6R,7R)-
• 7β-[2-(2-Aminothiazol-4-yl-(Z)-2-(methoxyimino)acetamido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid
• Antibiotic L-105
• Cefuzoname
• Cl 118523
• Cl 251931
• L 105
• L 105 (cephem antibiotic)

Cefuzonam

CAS: 82219-78-1

Formula: C₁₆H₁₅N₇O₅S₄

Purity: 95%

Molecular weight: 513.5942

Ref: IN-DA00G258

Cefuzonam

CAS: 82219-78-1

Cefuzonam

Purity: ≥95%

Molecular weight: 513.59g/mol

Ref: 54-BUP01051

Cefuzonam

CAS: 82219-78-1

Cefazolin is a novel cephalosporin with anti-inflammatory activity and may be used in studies of respiratory tract infections and hepatobiliary infections.

Formula: C₁₆H₁₅N₇O₅S₄

Purity: 97.79% - 99.60%

Color and Shape: Solid

Molecular weight: 513.59

Ref: TM-T67978

Cefuzonam

CAS: 82219-78-1

Formula: C₁₆H₁₅N₇O₅S₄

Molecular weight: 513.59

Ref: 7W-GA3453