CAS 823178-43-4

Anagrelide hcl monohydrate

Description:

Anagrelide hydrochloride monohydrate is a pharmaceutical compound primarily used as a platelet-reducing agent in the treatment of essential thrombocythemia, a condition characterized by an overproduction of platelets. It functions as a selective inhibitor of megakaryocyte maturation, thereby reducing platelet counts in the bloodstream. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in a clinical setting. Its chemical structure includes a pyrimidinone core, contributing to its biological activity. Anagrelide is typically administered orally, and its pharmacokinetics involve metabolism primarily in the liver, with renal excretion of its metabolites. Common side effects may include headache, palpitations, and gastrointestinal disturbances. As with any medication, it is essential to monitor patients for potential adverse reactions and interactions with other drugs. Overall, Anagrelide hydrochloride monohydrate plays a crucial role in managing conditions associated with elevated platelet levels, improving patient outcomes when used appropriately.

Anagrelide Hydrochloride

CAS: 823178-43-4

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₀H₇Cl₂N₃O·HCl·H₂O

Color and Shape: Off-White White Powder

Molecular weight: 254.99662

Ref: 45-1034738

6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride hydrate

CAS: 823178-43-4

6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one hydrochloride hydrate

Purity: 98%

Molecular weight: 310.57g/mol

Ref: 54-OR1063001

Anagrelide hydrochloride monohydrate

CAS: 823178-43-4

Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.

Formula: C₁₀H₁₀Cl₃N₃O₂

Color and Shape: Solid

Molecular weight: 310.56

Ref: TM-T75293

Anagrelide Hydrochloride Monohydrate

Controlled Product

CAS: 823178-43-4

Formula: C₁₀H₇Cl₂N₃O·ClH·H₂O

Color and Shape: Neat

Molecular weight: 310.564

Ref: TR-A641028

Anagrelide hydrochloride monohydrate

CAS: 823178-43-4

Anagrelide hydrochloride monohydrate is a synthetic drug that has been shown to be effective in the treatment of cardiovascular diseases and myeloproliferative disorder. It is also used as a prophylactic agent for thromboembolic disorders. Anagrelide hydrochloride monohydrate is used to prevent complications when patients are undergoing surgery, or are at risk for developing deep vein thrombosis or pulmonary embolism. The dosage range is usually between 0.2mg/kg and 1mg/kg, with an average dose of 0.5 mg/kg. In some cases, doses may be increased to 2 mg/kg, if needed. Anagrelide hydrochloride monohydrate belongs to the class of drugs known as phosphodiesterase inhibitors that work by preventing the breakdown of cyclic AMP (cAMP). Anagrelide hydrochloride monohydrate also inhibits the activity of cyclic GMP phosphodiesterase, which

Formula: C₁₀H₇Cl₂N₃O•HCl•H₂O

Purity: Min. 95%

Molecular weight: 310.56 g/mol

Ref: 3D-YHB17843