CAS 823780-39-8

Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-leucyl-

Description:

Glycine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-leucyl-, commonly referred to as Fmoc-D-Leu-Gly, is a synthetic peptide derivative used primarily in peptide synthesis and research. This compound features a glycine residue linked to a D-leucine moiety, with a fluorenylmethoxycarbonyl (Fmoc) protecting group that is commonly employed in solid-phase peptide synthesis. The Fmoc group provides stability during synthesis and can be easily removed under basic conditions, allowing for the subsequent coupling of additional amino acids. The presence of the D-leucine is significant as it introduces chirality and can influence the peptide's conformation and biological activity. This compound is typically characterized by its solubility in organic solvents and its stability under standard laboratory conditions. Its applications extend to the development of peptide-based drugs and in the study of protein interactions, making it a valuable tool in biochemistry and medicinal chemistry.

Formula: C₂₃H₂₆N₂O₅