CAS 82398-34-3

Diaquo[(1R,2R)-1,2-cyclohexanediaMine]platinuM DiMer Dinitrate

Description:

Diaquo[(1R,2R)-1,2-cyclohexanediamine]platinum dimer dinitrate is a platinum-based coordination compound characterized by its unique structure and properties. This compound features a platinum center coordinated to two bidentate ligands, specifically (1R,2R)-1,2-cyclohexanediamine, which imparts chirality to the complex. The presence of two aqua ligands enhances its solubility in aqueous environments. As a dimer, it consists of two platinum units linked together, which can influence its reactivity and stability. The dinitrate groups serve as counterions, contributing to the overall charge balance of the compound. Such platinum complexes are of interest in medicinal chemistry, particularly in the development of anticancer agents, due to their ability to interact with DNA. The stereochemistry of the cyclohexanediamine ligands can affect the biological activity and pharmacokinetics of the compound. Overall, Diaquo[(1R,2R)-1,2-cyclohexanediamine]platinum dimer dinitrate exemplifies the intricate relationship between coordination chemistry and biological applications.

Formula: C₁₂H₂₄N₄O₂Pt₂

Synonyms:

• Oxaliplatin Impurity 5 Dinitrate（Oxaliplatin EP Impurity E Dinitrate）
• Oxaliplatin Impurity E
• Oxaliplatin Impurity 2
• dioxidanium,(1R,2R)-cyclohexane-1,2-diamine,platinum,dinitrate
• Diaquo[(1R,2R)-1,2-cyclohexanediaMine]platinuM DiMer Dinitrate
• Diaquodiaminocyclohexaneplatinum Dimer Dinitrate
• Oxaliplatin EP Impurity E Dinitrate

Oxaliplatin Impurity 2

CAS: 82398-34-3

Formula: C₁₂H₂₆N₄O₂Pt₂₂NO₃

Molecular weight: 648.55 2x62.01

Ref: 4Z-O-245

Diaquo[(1R,2R)-1,2-cyclohexanediamine]platinum Dimer Dinitrate

Controlled Product

CAS: 82398-34-3

Impurity Oxaliplatin EP Impurity E
Stability Light Sensitive
Applications A dimeric impurity of Oxaliplatin (O845075) with neoplasm-inhibiting activity.
References Gill, D.: Dev. Oncol., 17, 267 (1984);

Formula: C₁₂H₃₀N₆O₈Pt₂

Color and Shape: White To Light Yellow

Molecular weight: 776.56

Ref: TR-D416765

Oxaliplatin Impurity E

CAS: 82398-34-3

Oxaliplatin Impurity E is a drug product, which is an impurity that was discovered in the synthesis of oxaliplatin. It is a metabolite and an impurity standard for HPLC. Oxaliplatin Impurity E has been shown to inhibit the growth of cancer cells and may be used as a chemopreventive agent. Research is currently being conducted to determine how this compound interacts with the body's natural processes.

Formula: C₁₂H₃₀N₆O₈Pt₂

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 776.57 g/mol

Ref: 3D-IO159550

Oxaliplatin EP Impurity E

CAS: 82398-34-3

Formula: C₁₂H₂₈N₄O₂Pt₂(NO₃)

Molecular weight: 650.6 : 2(62.01)

Ref: ST-EA-CP-O12005