CAS 82414-35-5

N1,N8-DIACETYLSPERMIDINE

Description:

N1,N8-Diacetylspermidine is a polyamine compound characterized by the presence of two acetyl groups attached to the nitrogen atoms at positions 1 and 8 of the spermidine backbone. This compound is a derivative of spermidine, which is a naturally occurring polyamine involved in cellular processes such as cell growth, differentiation, and apoptosis. N1,N8-Diacetylspermidine is typically a white to off-white solid and is soluble in polar solvents. Its molecular structure contributes to its biological activity, as polyamines play crucial roles in cellular functions and are implicated in various physiological and pathological processes. The compound is of interest in biochemical research, particularly in studies related to cell proliferation and cancer. Additionally, it may serve as a potential biomarker or therapeutic target due to its involvement in cellular metabolism. As with many chemical substances, handling should be done with care, following appropriate safety protocols to mitigate any potential hazards.

Formula: C₁₁H₂₃N₃O₂

Synonyms:

• N1,N8-DIACETYLSPERMIDINE
• N1,8-Diacetylspermidine
• N-[3-[[4-(Acetylamino)butyl]amino]propyl]acetamide

N1,N8-Diacetylspermidine

CAS: 82414-35-5

N1,N8-Diacetylspermidine

Purity: ≥98%

Molecular weight: 229.32g/mol

Ref: 54-BUP21191

N1,N8-Diacetylspermidine

CAS: 82414-35-5

N1,N8-Diacetylspermidine is a polyamine found in human urine.N1,N8-Diacetylspermidine can be used as a marker for cancer and malignancy.

Formula: C₁₁H₂₃N₃O₂

Purity: 99.9% - >99.99%

Color and Shape: Solid

Molecular weight: 229.32

Ref: TM-T19461

N1,N8-Diacetylspermidine

Controlled Product

CAS: 82414-35-5

Applications N1,N8-Diacetylspermidine is a diacetylated derivative of Spermidine (S680400) found in urine and is a novel promising tumor marker for breast and colorectal cancer.
References Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006)

Formula: C₁₁H₂₃N₃O₂

Color and Shape: Neat

Molecular weight: 229.32

Ref: TR-D367000

N1,N8-Diacetylspermidine

CAS: 82414-35-5

N1,N8-Diacetylspermidine is a cell-permeable inhibitor of protein interactions that has been used as a research tool to study protein interactions. This compound binds to the receptor and activates it by blocking the binding of ligands. N1,N8-Diacetylspermidine is a ligand for the acetylcholine receptor. The binding of this compound to the acetylcholine receptor leads to activation and subsequent opening of ion channels in nerve cells, which leads to an increase in the rate of neurotransmitter release. N1,N8-Diacetylspermidine has also been shown to activate another type of receptor called the nicotinic acetylcholine receptor, which is found in both insects and mammals. This activation can lead to increased levels of glutamate in synapses, leading to long-term potentiation (LTP) or long-term depression (LTD).

Formula: C₁₁H₂₃N₃O₂

Purity: Min. 95%

Molecular weight: 229.32 g/mol

Ref: 3D-HDA41435