CAS 82419-52-1

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-

Description:

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-, identified by CAS number 82419-52-1, is a complex organic compound characterized by its unique bicyclic structure that incorporates both a pyridine and a benzoxazine moiety. This compound features a carboxylic acid functional group, which contributes to its acidity and potential reactivity. The presence of a fluorine atom and a piperazine ring suggests that it may exhibit interesting pharmacological properties, potentially influencing its solubility and biological activity. The 7-oxo and 3-methyl substituents further modify its chemical behavior, possibly enhancing its interaction with biological targets. Such compounds are often investigated for their potential applications in medicinal chemistry, particularly in the development of pharmaceuticals. The structural complexity and functional groups present in this compound may also lead to diverse chemical reactivity, making it a subject of interest in synthetic organic chemistry and drug design.

Formula: C₁₇H₁₈FN₃O₄

Synonyms:

• Ofloxacin Related Compound A (25 Mg) ((Rs)-9-Fluoro-2,3-Dihydro-3-Methyl-7-Oxo-10-(Pipera-Zin-1 -Yl)-7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid)
• 9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid
• Desmethyl Ofloxacin
• 9-Fluoro-2,3-dihydro-3-methyl-7-oxo-10-(1-piperazinyl)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Hydrochloride
• Desmethyl Ofloxacin Hydrochloride

Desmethylofloxacin

CAS: 82419-52-1

Color and Shape: Neat

Ref: 61-FOR0228.08

Ofloxacin Related Compound A (9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid)

CAS: 82419-52-1

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₇H₁₈FN₃O₄

Color and Shape: Light Yellow Powder

Molecular weight: 347.12813

Ref: 45-1478119

Ofloxacin EP Impurity E (Ofloxacin USP Related Compound A)

CAS: 82419-52-1

Formula: C₁₇H₁₈FN₃O₄

Molecular weight: 347.35

Ref: 4Z-O-034005

(RS)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid

Controlled Product

CAS: 82419-52-1

Formula: C₁₇H₁₈FN₃O₄

Color and Shape: Neat

Molecular weight: 347.34

Ref: 86-MM0228.08

Desmethyl Ofloxacin

Controlled Product

CAS: 82419-52-1

Impurity Ofloxacin EP Impurity E
Applications Desmethyl Ofloxacin (Ofloxacin EP Impurity E) is a metabolite of Ofoxacin (O245750), a fluorinated quinolone antibacterial.
References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989); Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991); Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994); Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)

Formula: C₁₇H₁₈FN₃O₄

Color and Shape: White To Light Beige

Molecular weight: 347.34

Ref: TR-D292270

Desmethyl ofloxacin

CAS: 82419-52-1

Desmethyl ofloxacin is a metabolite of ofloxacin, which is a fluoroquinolone antibiotic. Ofloxacin inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Desmethyl ofloxacin has been shown to have pharmacokinetic properties that are similar to those of the parent drug and can be used as an alternative for the treatment of urinary tract infections.

Formula: C₁₇H₁₈FN₃O₄

Purity: Min. 95%

Molecular weight: 347.34 g/mol

Ref: 3D-FD21301

Ofloxacin EP Impurity E

CAS: 82419-52-1

Formula: C₁₇H₁₈FN₃O₄

Molecular weight: 347.34

Ref: ST-EA-CP-O5005