CAS 824932-89-0

3-(4-Hydroxy-3,5-dimethylphenyl)-1-[4-(methylthio)phenyl]-2-propen-1-one

Description:

3-(4-Hydroxy-3,5-dimethylphenyl)-1-[4-(methylthio)phenyl]-2-propen-1-one, with the CAS number 824932-89-0, is an organic compound characterized by its complex structure that includes a propenone moiety, which is a conjugated system that can exhibit both electrophilic and nucleophilic properties. This compound features a hydroxyl group, which can participate in hydrogen bonding, enhancing its solubility in polar solvents. The presence of methylthio and dimethylphenyl groups contributes to its hydrophobic characteristics, potentially influencing its biological activity and interactions. The compound may exhibit antioxidant properties due to the presence of the hydroxyl group, and its structural features suggest potential applications in pharmaceuticals or as a dye. Additionally, the compound's reactivity can be influenced by the electron-donating and withdrawing effects of its substituents, making it a candidate for further studies in organic synthesis and medicinal chemistry. Overall, its unique combination of functional groups and structural elements makes it a subject of interest in various chemical research fields.

Formula: C₁₈H₁₈O₂S

InChI: InChI=1S/C18H18O2S/c1-12-10-14(11-13(2)18(12)20)4-9-17(19)15-5-7-16(21-3)8-6-15/h4-11,20H,1-3H3

InChI key: InChIKey=PHRSDLZWVTXEOY-UHFFFAOYSA-N

SMILES: C(C=CC1=CC(C)=C(O)C(C)=C1)(=O)C2=CC=C(SC)C=C2

Synonyms:

• 1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one
• 2-Propen-1-one, 3-(4-hydroxy-3,5-dimethylphenyl)-1-[4-(methylthio)phenyl]-
• 3-(4-Hydroxy-3,5-dimethylphenyl)-1-[4-(methylthio)phenyl]-2-propen-1-one

2-Propen-1-one, 3-(4-hydroxy-3,5-dimethylphenyl)-1-[4-(methylthio)phenyl]-

CAS: 824932-89-0

Formula: C₁₈H₁₈O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.3993

Ref: IN-DA00G3S4

1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one

CAS: 824932-89-0

1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one

Purity: 98%

Molecular weight: 298.41g/mol

Ref: 54-OR1032045

1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one

CAS: 824932-89-0

Purity: 98%

Molecular weight: 298.4

Ref: 10-F986472

1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one

Controlled Product

CAS: 824932-89-0

Applications 1-(4-Methylthiophenyl)-3-(3,5-dimethyl-4-hydroxyphenyl)prop-2-en-1-one is an intermediate in synthesizing GFT-505 (G368870), which is a dual PPARα/δ agonist. Studies have shown that GFT-505 improves hepatic and peripheral insulin sensitivity in abdominally obese subjects. It may also be a potential new drug candidate for treating lipid and glucose disorders.
References Carious, B., et al.: Diabetes Care 36, 2923 (2013); Carious, B., et al.: Diabetes Care 34, 2008 (2011);

Formula: C₁₈H₁₈O₂S

Color and Shape: Neat

Molecular weight: 298.4

Ref: TR-M331405