CAS 82508-37-0

Deacetylpseudolaric acid A

Description:

Deacetylpseudolaric acid A is a natural compound derived from the bark of the Pseudolarix amabilis tree, commonly known as the golden larch. This compound belongs to the class of diterpenoids and is characterized by its complex molecular structure, which includes multiple rings and functional groups. It exhibits a range of biological activities, including anti-inflammatory, anti-tumor, and anti-viral properties, making it of interest in pharmaceutical research. The substance is typically studied for its potential therapeutic applications, particularly in cancer treatment and as an anti-inflammatory agent. Its mechanism of action often involves the modulation of various signaling pathways within cells. Additionally, Deacetylpseudolaric acid A is known for its relatively low toxicity, which enhances its appeal for further development in medicinal chemistry. As with many natural products, the extraction and purification processes can be challenging, and ongoing research aims to optimize these methods while exploring its full pharmacological potential.

Formula: C₂₀H₂₆O₅

InChI: InChI=1S/C20H26O5/c1-13-6-10-19-11-8-15(20(19,24)12-7-13)18(3,25-17(19)23)9-4-5-14(2)16(21)22/h4-6,9,15,24H,7-8,10-12H2,1-3H3,(H,21,22)/b9-4+,14-5+/t15-,18+,19+,20-/m0/s1

InChI key: InChIKey=MQOMHFMKUJFDBH-SWRVIOJRSA-N

SMILES: O[C@]12[C@]3(C(=O)O[C@@](/C=C/C=C(/C(O)=O)\C)(C)[C@@]1(CC3)[H])CC=C(C)CC2

Synonyms:

• 2,4-Pentadienoic acid, 5-[(3R,4R,4aS,9aR)-3,4,4a,5,6,9-hexahydro-4a-hydroxy-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl]-2-methyl-, (2E,4E)-
• 2,4-Pentadienoic acid, 5-(3,4,4a,5,6,9-hexahydro-4a-hydroxy-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl)-2-methyl-, [3α(2E,4E),4α,4aα,9aα]-
• (2E,4E)-5-[(3R,4R,4aS,9aR)-3,4,4a,5,6,9-Hexahydro-4a-hydroxy-3,7-dimethyl-1-oxo-1H-4,9a-ethanocyclohepta[c]pyran-3-yl]-2-methyl-2,4-pentadienoic acid
• Deacetylpseudolaric acid A
• 1H-4,9a-Ethanocyclohepta[c]pyran, 2,4-pentadienoic acid deriv.
• Deacetylpseudolaric acid A（(-)-Deacetylpseudolaric acid A）

Deacetylpseudolaric acid A

CAS: 82508-37-0

Formula: C₂₀H₂₆O₅

Purity: 98%

Molecular weight: 346.4174

Ref: IN-DA00G673

Deacetylpseudolaric acid A

CAS: 82508-37-0

Deacetylpseudolaric acid A is a natural product from Pseudolarix amabilis.

Formula: C₂₀H₂₆O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 346.42

Ref: TM-TN1554

Deacetylpseudolaric acid A

CAS: 82508-37-0

Formula: C₂₀H₂₆O₅

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 346.423

Ref: BP-SBP00438

Deacetylpseudolaric acid A

CAS: 82508-37-0

Deacetylpseudolaric acid A is a diterpenoid compound, which is derived from the Pseudolarix genus of trees, notably Pseudolarix amabilis (also known as the golden larch). It exhibits its mode of action by targeting cellular microtubules, disrupting tubulin polymerization, a key component of the cytoskeleton critical for cell division. This disruption impedes the mitotic process, inducing cell cycle arrest and promoting apoptosis in cancer cells. As a consequence, deacetylpseudolaric acid A has garnered interest for its potential applications in cancer therapy. Its unique mechanism of action allows it to be considered for use in overcoming multidrug resistance, a major hurdle in effective cancer treatment. Moreover, due to its targeted action, research continues to explore its efficacy against a variety of cancer cell lines, and its potential synergistic effects when used in combination with other anticancer agents. Studies also examine its pharmacokinetics and favorable therapeutic indices, paving the way for future clinical applications and drug development.

Formula: C₂₀H₂₆O₅

Purity: Min. 95%

Molecular weight: 346.4 g/mol

Ref: 3D-HDA50837