CAS 82547-81-7

Cefteram pivoxil

Description:

Cefteram pivoxil is a broad-spectrum cephalosporin antibiotic, primarily used to treat various bacterial infections. It is a prodrug, meaning it is converted into its active form, cefteram, in the body. This compound exhibits a high affinity for penicillin-binding proteins, which are essential for bacterial cell wall synthesis, thereby inhibiting bacterial growth. Cefteram pivoxil is effective against both Gram-positive and Gram-negative bacteria, making it versatile in clinical applications. It is typically administered orally and is known for its good bioavailability. The substance is characterized by its stability in the presence of beta-lactamases, enzymes produced by some bacteria that confer resistance to other antibiotics. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe hypersensitivity reactions. As with all antibiotics, it is crucial to use cefteram pivoxil judiciously to minimize the risk of developing antibiotic resistance.

Formula: C₂₂H₂₇N₉O₇S₂

InChI: InChI=1S/C22H27N9O7S2/c1-10-26-29-30(27-10)6-11-7-39-18-14(25-16(32)13(28-36-5)12-8-40-21(23)24-12)17(33)31(18)15(11)19(34)37-9-38-20(35)22(2,3)4/h8,14,18H,6-7,9H2,1-5H3,(H2,23,24)(H,25,32)/b28-13-/t14-,18-/m1/s1

InChI key: InChIKey=UIYAXIPXULMHAI-JLGRZTKVSA-N

SMILES: C(OCOC(C(C)(C)C)=O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1CN4N=C(C)N=N4)[H]

Synonyms:

• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
• Antibiotic T 2588
• Cefteram Pivoxila
• Pivaloyloxymethyl (Z)-7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-(5-methyl-2H-tetrazol-2-ylmethyl)-3-cephem-4-carboxylate
• Ro 19-5248
• T 2588
• Tomiron
• Tomiron 100
• [(2,2-dimethylpropanoyl)oxy]methyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefteram Pivoxil

CAS: 82547-81-7

Formula: C₂₂H₂₇N₉O₇S₂

Molecular weight: 593.64

Ref: 4Z-C-893

Cefteram pivoxil

CAS: 82547-81-7

Cefteram pivoxil (T-2588, CFTM-PI), an oral antibiotic in powder and tablet forms, treats bacterial infections in China.

Formula: C₂₂H₂₇N₉O₇S₂

Purity: 91.32%

Color and Shape: Solid

Molecular weight: 593.64

Ref: TM-T22287

Cefteram Pivoxil

Controlled Product

CAS: 82547-81-7

Applications Third generation, orally active cephalosporin antibiotic. Antibacterial.
References Wise, R., et al.: Antimicrob. Agents Chemother., 29, 1067 (1986), Hirai, S., et al.: Jpn. J. Antibiot., 39, 958 (1986), Lentz, K., et al.: Int. J. Pharm., 200, 41 (2000), Takagi, T., et al.: Mol. Pharmaceutics, 3, 631 (2006), Gu, C., et al.: Pharm. Res., 24, 1118 (2007),

Formula: C₂₂H₂₇N₉O₇S₂

Color and Shape: Neat

Molecular weight: 593.64

Ref: TR-C244300

Cefteram pivoxil

CAS: 82547-81-7

Cefteram pivoxil is an oral prodrug that is converted to the active form, ceftriaxone, in vivo. It is used for the treatment of bacterial infections and has anti-inflammatory properties. Cefteram pivoxil possesses a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including penicillinase-producing strains such as Staphylococcus aureus and Enterobacter spp., as well as enterococci and streptococci. This drug also shows good efficacy against E. coli, Klebsiella pneumoniae, Citrobacter spp., Proteus mirabilis, Pseudomonas aeruginosa, H. influenzae, and Bacteroides fragilis. As an oral cephalosporin antibiotic, cefteram pivoxil has been shown to be safe for use in children with inflammatory bowel disease or cystic fibrosis. Cefteram pivox

Formula: C₂₂H₂₇N₉O₇S₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 593.64 g/mol

Ref: 3D-FC19875

Cefteram Pivoxil

CAS: 82547-81-7

Formula: C₂₂H₂₇N₉O₇S₂

Molecular weight: 593.6

Ref: ST-EA-CP-C214001