CAS 82626-48-0

Zolpidem

Description:

Zolpidem is a non-benzodiazepine sedative-hypnotic medication primarily used for the short-term treatment of insomnia. It acts on the central nervous system by selectively binding to the GABA-A receptor, enhancing the inhibitory effects of gamma-aminobutyric acid (GABA), which promotes sleep. Zolpidem is characterized by its rapid onset of action, typically within 30 minutes, and a relatively short half-life, making it effective for initiating sleep but less suitable for maintaining sleep. The substance is usually administered in oral form, available in immediate-release and extended-release formulations. Common side effects may include drowsiness, dizziness, and potential for dependence with prolonged use. Due to its sedative properties, caution is advised when operating machinery or driving after taking Zolpidem. It is classified as a Schedule IV controlled substance in many jurisdictions due to its potential for abuse and dependence. Overall, Zolpidem is an important pharmacological option for managing sleep disorders, but it should be used under medical supervision to mitigate risks associated with its use.

Formula: C₁₉H₂₁N₃O

InChI: InChI=1/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3

InChI key: InChIKey=ZAFYATHCZYHLPB-UHFFFAOYSA-N

SMILES: C(C(N(C)C)=O)C1=C(N=C2N1C=C(C)C=C2)C3=CC=C(C)C=C3

Synonyms:

• Edluar
• N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-a]pyridine-3-acetamide
• Nytamel
• Sl 80-0750
• Sl 800750
• Zoldem
• Zolnod
• Zolpidem
• Imidazo[1,2-a]pyridine-3-acetamide, N,N,6-trimethyl-2-(4-methylphenyl)-
• N,N,6-Trimethyl-2-p-tolylimidazo[1,2-a]pyridine-3-acetamide
• N,N-Dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide
• N,N,6-Trimethyl-2-(4-methylphenyl)imidazo[1,2-
• ZOLPIDEM >96% IMIDAZOPYRIDINE DERIV
• Niotal
• Stilnoct：Stilnox
• 6-methyl-N,N-dimethyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyridine-3-yl]-acetamide (intermediate of zolpidem)
• SL-80．0750-23N
• N,N-dimethyl-2-[3-methyl-8-(4-methylphenyl)-1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-9-yl]acetamide
• 6-METHYL-N,N-DIMETHYL-2-(4-METHYL-PHENYL)-IMIDAZO[1,2-A]PYRIDINE-3-YL]-ACETAMIDE
• 2-a)pyridine-3-acetamide,2-(4-methylphenyl)-n,n,6-trimethyl-imidazo(
• N,N,6-TRIMETHYL-2-(4-METHYLPHENYL)-IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE HEMITARTRATE
• N,N,6-TRIMETHYL-2-(4-METHYLPHENYL)IMIDAZO[1,2-A]PYRIMIDINE-3-ACETAMIDE
• Ivadal
• 2-(4-Methylphenyl)-6-Methylimidazo(1,2,a)Pyridine

Zolpidem

Controlled Product

CAS: 82626-48-0

Applications A selective non-benzodiazepine GABAA receptor agonist. Sedative, hypnotic. Controlled substance (depresssant).
References Arbilla, S., et al.: Arch. Pharmacol., 330, 248 (1985), Cashman, J.N., et al.: Brit. J. Clin. Pharmacol., 21, 205 (1986)

Formula: C₁₉H₂₁N₃O

Color and Shape: Off-White

Molecular weight: 307.39

Ref: TR-Z650000

Zolpidem

Controlled Product

CAS: 82626-48-0

Zolpidem is a nonbenzodiazepine hypnotic drug that is used in the treatment of insomnia. Zolpidem is effective for the treatment of insomnia as it binds to receptors in the brain, which enhances GABA function. Zolpidem has a low potential for abuse and dependence and can be used as an alternative to benzodiazepines. It also has few side-effects, such as dizziness, headache, nausea, diarrhea, and constipation. The most common side-effect is drowsiness or sedation. Zolpidem may potentiate the effects of other drugs with similar binding profiles and induce high values in wastewater treatment facilities. These drugs include triazolam and α1 subunit blockers.

Formula: C₁₉H₂₁N₃O

Purity: Min. 95%

Molecular weight: 307.39 g/mol

Ref: 3D-ID57819

Zolpidem CIV

Controlled Product

CAS: 82626-48-0

Anticonvulsants, hypnotics and sedatives

Formula: C₁₉H₂₁N₃O

Color and Shape: Powder

Molecular weight: 307.16846

Ref: 45-1724893