CAS 827-44-1

5-chloro-3-phenyl-1,2,4-oxadiazole

Description:

5-Chloro-3-phenyl-1,2,4-oxadiazole is a heterocyclic organic compound characterized by its oxadiazole ring, which consists of two nitrogen atoms and one oxygen atom within a five-membered ring structure. The presence of a chlorine atom at the 5-position and a phenyl group at the 3-position contributes to its unique chemical properties. This compound typically exhibits moderate solubility in organic solvents and may show limited solubility in water due to its hydrophobic phenyl group. It is known for its potential applications in pharmaceuticals, agrochemicals, and materials science, particularly in the development of dyes and fluorescent compounds. The oxadiazole moiety is often associated with biological activity, making this compound of interest in medicinal chemistry. Additionally, its stability and reactivity can be influenced by the substituents on the ring, which can affect its electronic properties and interactions with other molecules. Overall, 5-chloro-3-phenyl-1,2,4-oxadiazole is a versatile compound with significant implications in various fields of research.

Formula: C₈H₅ClN₂O

InChI: InChI=1/C8H5ClN2O/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H

SMILES: c1ccc(cc1)c1nc(Cl)on1

5-chloro-3-phenyl-1,2,4-oxadiazole

CAS: 827-44-1

Formula: C₈H₅ClN₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 180.5911

Ref: IN-DA00G4GZ

5-Chloro-3-phenyl-[1,2,4]oxadiazole

CAS: 827-44-1

5-Chloro-3-phenyl-[1,2,4]oxadiazole

Molecular weight: 180.59g/mol

Ref: 54-OR346247

5-chloro-3-phenyl-1,2,4-oxadiazole

CAS: 827-44-1

Formula: C₈H₅ClN₂O

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 180.59

Ref: 10-F312079

5-Chloro-3-phenyl-1,2,4-oxadiazole

CAS: 827-44-1

5-Chloro-3-phenyl-1,2,4-oxadiazole is a potent and selective inhibitor of fatty acid amide hydrolase (FAAH). It is also an inhibitor of the permeability glycoprotein PGP. 5-Chloro-3-phenyl-1,2,4-oxadiazole has a potent inhibitory activity against FAAH and PGP at low concentrations. This inhibition can be improved by optimization of the lead compound. 5-Chloro-3-phenyl-1,2,4-oxadiazole is orally active in rats and in humans. In animal studies it has been shown to produce dose dependent effects on blood pressure and heart rate when administered intravenously or orally.

Formula: C₈H₅ClN₂O

Purity: Min. 95%

Molecular weight: 180.59 g/mol

Ref: 3D-FC126633