CAS 827026-45-9

3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione

Description:

3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione, with the CAS number 827026-45-9, is a chemical compound characterized by its complex structure, which includes a piperidine ring and an isoindole moiety. The presence of a nitro group and a carbonyl group contributes to its reactivity and potential biological activity. This compound may exhibit properties such as being a potential pharmacophore in medicinal chemistry, given its structural features that can interact with biological targets. The piperidine ring typically imparts basicity, while the diketone functionality can participate in various chemical reactions, including condensation and nucleophilic attacks. Additionally, the nitro group can influence the compound's electronic properties and solubility. Overall, this substance may be of interest in research fields such as drug development, organic synthesis, and materials science, although specific applications would depend on further studies and evaluations of its biological activity and stability.

Formula: C₁₃H₁₁N₃O₅

InChI: InChI=1/C13H11N3O5/c17-11-5-4-10(12(18)14-11)15-6-8-7(13(15)19)2-1-3-9(8)16(20)21/h1-3,10H,4-6H2,(H,14,17,18)

SMILES: c1cc2c(CN(C3CCC(=NC3=O)O)C2=O)c(c1)N(=O)=O

Synonyms:

• 2,6-piperidinedione, 3-(1,3-dihydro-4-nitro-1-oxo-2H-isoindol-2-yl)-
• 3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidin-2,6-dion
• 3-(4-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
• 3-(4-Nitro-1-Oxoisoindolin-2-Yl)Piperidine-2,6-Dione

(3S)-3-(4-Nitro-1-oxo-1,3-dihydro-2h-isoindol-2-yl)piperidine-2,6-dione

CAS: 827026-45-9

Formula: C₁₃H₁₁N₃O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 289.2435

Ref: IN-DA0036GJ

Lenalidomide Impurity 28

CAS: 827026-45-9

Formula: C₁₃H₁₁N₃O₅

Color and Shape: White To Off-White Solid

Molecular weight: 289.25

Ref: 4Z-L-263

3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione

CAS: 827026-45-9

3-(4-Nitro-1-oxo-1,3-dihydroisoindol-2-yl)piperidine-2,6-dione

Purity: 99%

Molecular weight: 289.24g/mol

Ref: 54-OR79449

3-(4-Nitro-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione (4-Nitro Analogue of Lenalidomide)

Controlled Product

CAS: 827026-45-9

Formula: C₁₃H₁₁N₃O₅

Color and Shape: Neat

Molecular weight: 289.24

Ref: 86-MM3641.02

4-Nitro Lenalidomide

Controlled Product

CAS: 827026-45-9

Impurity Lenalidomide impurity
Applications Lenalidomide (L328000) analog. Lenalidomide impurity; Lenalidomide intermediate.
References Hashimoto, Y., et al.: Bioorg. Med. Chem., 10, 461 (2002),

Formula: C₁₃H₁₁N₃O₅

Color and Shape: Neat

Molecular weight: 289.24

Ref: TR-N496395

Lenalidomide 4-Nitro Impurity

CAS: 827026-45-9

Formula: C₁₃H₁₁N₃O₅

Molecular weight: 289.24

Ref: ST-EA-CP-L27001

3-(4-Nitro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

CAS: 827026-45-9

Formula: C₁₃H₁₁N₃O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 289.247

Ref: 10-F232168

4-Nitro lenalidomide

CAS: 827026-45-9

4-Nitro lenalidomide is an organic compound that is a derivative of the drug lenalidomide. It is synthesized by reacting 2-nitrobenzaldehyde with amines, yielding 4-nitro-N-(2-chloroethyl)-N-(2,3-dihydroxypropyl)benzamide or 4-nitrolenalidomide. This reaction occurs in tetrahydrofuran (THF) as a solvent and in the presence of sodium borohydride (NaBH4). The four nitro groups are used to control the enantiomeric purity of the product. The chemical formula for 4-nitro lenalidomide is C12H14ClNO2.

Formula: C₁₃H₁₁N₃O₅

Purity: Min. 95%

Molecular weight: 289.24 g/mol

Ref: 3D-FN26234