CAS 82747-56-6

3-(4-chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride (1:1)

Description:

3-(4-Chlorophenyl)-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride is a chemical compound characterized by its complex bicyclic structure, which includes a furo[3,4-c]pyridine framework. This substance features a chlorophenyl group and a hydroxyl group, contributing to its potential biological activity. The hydrochloride salt form indicates that it is a hydrochloride, which enhances its solubility in water and may influence its pharmacokinetic properties. The presence of the methyl group and the chlorophenyl moiety suggests that it may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. The compound is likely to be a solid at room temperature and may have specific melting and boiling points, as well as solubility characteristics that are typical for similar organic compounds. Its CAS number, 82747-56-6, allows for precise identification in chemical databases and literature. Overall, this compound's unique structure and functional groups may contribute to its potential applications in pharmaceuticals or other chemical research areas.

Formula: C₁₄H₁₃Cl₂NO₂

InChI: InChI=1/C14H12ClNO2.ClH/c1-8-13(17)12-7-18-14(11(12)6-16-8)9-2-4-10(15)5-3-9;/h2-6,14,17H,7H2,1H3;1H

SMILES: Cc1c(c2COC(c3ccc(cc3)Cl)c2cn1)O.Cl

Synonyms:

• Cicletanine Hydrochloride
• Furo(3,4-c)pyridin-7-ol, 3-(4-chlorophenyl)-1,3-dihydro-6-methyl-, hydrochloride

Cicletanine Hydrochloride

CAS: 82747-56-6

Formula: C₁₄H₁₃Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 298.1645

Ref: IN-DA00582P

Cicletanine Hydrochloride

CAS: 82747-56-6

Applications A new antihypertensive agent; exhibited a natriuretic effect comparable to that of hydrochlorothiazide and furosemide within 7 h. A furopyridine derivative with antihypertensive and diuretic properties.
References Braquet, P., et al.: Lancet, 1, 1218 (1983), Guinot, P., et al.: Arzneim.-Forsch., 35, 1714 (1985), Clement, D., et al.: Int. J. Clin. Pharmacol. Res., 8, 9 (1988), Lize, J.M., et al.: Therapie, 42, 399 (1987),

Formula: C₁₄H₁₂ClNO₂·ClH

Color and Shape: Pink Solid

Molecular weight: 298.16

Ref: TR-C432700

Cicletanine hydrochloride

CAS: 82747-56-6

Cicletanine hydrochloride is a drug that has been shown to be effective in the treatment of pulmonary hypertension. It is a prodrug that is converted to cicletanine, which inhibits the activity of the cytosolic calcium-calmodulin-dependent protein kinase II (CaM kinase II). Cicletanine hydrochloride has been shown to have cardiac effects in vivo and to reduce cardiac contractility. This compound has potential side effects such as metabolic disorders, gastrointestinal problems, and fetal toxicity.

Formula: C₁₄H₁₃Cl₂NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 298.16 g/mol

Ref: 3D-FC20429