CAS 82816-76-0

N-T-boc-phe-phe-gly

Description:

N-T-boc-phe-phe-gly, also known as N-tert-butoxycarbonyl-L-phenylalanine-L-phenylalanine-glycine, is a protected amino acid derivative commonly used in peptide synthesis. The "N-T-boc" designation indicates that the amino group is protected by a tert-butoxycarbonyl (Boc) group, which is a common protective group in organic synthesis that can be removed under mild acidic conditions. The structure consists of two phenylalanine residues followed by a glycine, making it a dipeptide with a glycine tail. This compound is typically white to off-white in appearance and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol, but less soluble in water. Its applications are primarily in the field of peptide chemistry, where it serves as an intermediate in the synthesis of more complex peptides and proteins. The presence of the Boc group allows for selective reactions at the carboxyl or side-chain functional groups, facilitating the construction of larger peptide chains. Proper handling and storage conditions are essential to maintain its stability and reactivity.

Formula: C₂₅H₃₁N₃O₆

InChI: InChI=1/C25H31N3O6/c1-25(2,3)34-24(33)28-20(15-18-12-8-5-9-13-18)23(32)27-19(22(31)26-16-21(29)30)14-17-10-6-4-7-11-17/h4-13,19-20H,14-16H2,1-3H3,(H,26,31)(H,27,32)(H,28,33)(H,29,30)

SMILES: CC(C)(C)OC(=NC(Cc1ccccc1)C(=NC(Cc1ccccc1)C(=NCC(=O)O)O)O)O

Synonyms:

• Boc-Phe-Phe-Gly-OH
• N-(tert-butoxycarbonyl)phenylalanylphenylalanylglycine

Boc-Phe-Phe-Gly-OH

CAS: 82816-76-0

Boc-Phe-Phe-Gly-OH is a pentapeptide that has been modified to increase its hydrophobic properties. It also has a sequence of Boc-Phe-Phe-Gly, which is an affinity sequence for the binding of hydrophobic peptides to hydrophobic surfaces. The modifications and structural factors of this molecule contribute to its affinity for protein receptors and other molecules. These modifications are the n-terminal and c-terminal moieties. This pentapeptide has also been substituted with other amino acids in order to alter its sequence and function.

Formula: C₂₅H₃₁N₃O₆

Purity: Min. 95%

Molecular weight: 469.53 g/mol

Ref: 3D-FB111221