CAS 82834-16-0

Perindopril

Description:

Perindopril is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a prodrug that is converted in the body to its active form, perindoprilat. The chemical formula of perindopril is C19H32N2O5S, and it features a unique structure that includes a sulfonamide group, which is essential for its pharmacological activity. Perindopril is characterized by its ability to inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include cough, elevated potassium levels, and dizziness. As with other ACE inhibitors, it is contraindicated in pregnancy due to potential harm to the fetus. Overall, perindopril is an effective medication for managing cardiovascular conditions, contributing to improved patient outcomes in those with hypertension and heart failure.

Formula: C₁₉H₃₂N₂O₅

InChI: InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1

InChI key: InChIKey=IPVQLZZIHOAWMC-QXKUPLGCSA-N

SMILES: C([C@@H](N[C@H](C(OCC)=O)CCC)C)(=O)N1[C@@]2([C@](C[C@H]1C(O)=O)(CCCC2)[H])[H]

Synonyms:

• (2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic acid 1-ethyl ester
• (2S,3aS,7aS)-1-[(2R)-2-[[(1S)-1-Ethoxycarbonylbutyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
• (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid
• 1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-, (2S,3aS,7aS)-
• 1H-Indole-2-carboxylic acid, 1-[2-[[1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-, [2S-[1[R*(R*)],2α,3aβ,7aβ]]-
• API
• Adwepril
• McN-A 2833
• S 9490
• Perindopril

Perindopril

CAS: 82834-16-0

Formula: C₁₉H₃₂N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 368.4678

Ref: IN-DA008I5J

Perindopril-13C3

CAS: 82834-16-0

Formula: C₁₆₁₃C₃H₃₂N₂O₅

Molecular weight: 371.44

Ref: 4Z-P-063

Perindopril

CAS: 82834-16-0

Formula: C₁₉H₃₂N₂O₅

Molecular weight: 368.48

Ref: 4Z-P-062

Perindopril

Controlled Product

CAS: 82834-16-0

Formula: C₁₉H₃₂N₂O₅

Color and Shape: Off-White

Molecular weight: 368.47

Ref: 04-C15989750

Perindopril

CAS: 82834-16-0

Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.

Formula: C₁₉H₃₂N₂O₅

Color and Shape: White Powder

Molecular weight: 368.47

Ref: TM-T21485

Perindopril

Controlled Product

CAS: 82834-16-0

Applications An angiotensin-converting enzyme (ACE) inhibitor. Antihypertensive. Neuroprotective & Neuroresearch Product.
References Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987), Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)

Formula: C₁₉H₃₂N₂O₅

Color and Shape: Off-White

Molecular weight: 368.47

Ref: TR-P287500

Perindopril

CAS: 82834-16-0

Angiotensin-converting enzyme inhibitor

Formula: C₁₉H₃₂N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 368.47 g/mol

Ref: 3D-FP26845