CAS 82846-18-2

4-Fluoro-3-methoxybenzoic acid

Description:

4-Fluoro-3-methoxybenzoic acid is an aromatic carboxylic acid characterized by the presence of a fluorine atom and a methoxy group on a benzene ring. The molecular structure features a benzoic acid core, where the carboxylic acid (-COOH) group is attached to the aromatic ring, specifically at the para position relative to the fluorine substituent and the meta position relative to the methoxy group (-OCH3). This compound typically exhibits moderate solubility in organic solvents and limited solubility in water due to its hydrophobic aromatic structure. It may display acidic properties, allowing it to participate in various chemical reactions, including esterification and nucleophilic substitution. The presence of the fluorine atom can influence the compound's reactivity and polarity, while the methoxy group can affect its electronic properties and steric hindrance. 4-Fluoro-3-methoxybenzoic acid is of interest in pharmaceutical and chemical research, potentially serving as an intermediate in the synthesis of various biologically active compounds.

Formula: C₈H₇FO₃

InChI: InChI=1S/C8H7FO3/c1-12-7-4-5(8(10)11)2-3-6(7)9/h2-4H,1H3,(H,10,11)

InChI key: InChIKey=LWGCZCMLPRMKIZ-UHFFFAOYSA-N

SMILES: O(C)C1=CC(C(O)=O)=CC=C1F

Synonyms:

• 3-Methoxy-4-Fluorobenzoic Acid
• 4-Fluoro-m-anisic acid
• Benzoic acid, 4-fluoro-3-methoxy-
• Qvr Df Co1
• 4-Fluoro-3-methoxybenzoic acid

4-Fluoro-3-methoxybenzoic acid, 95%

CAS: 82846-18-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₇FO₃

Purity: 95%

Color and Shape: White to cream, Crystals or powder or crystalline powder

Molecular weight: 170.14

Ref: 02-L19673

3-Methoxy-4-fluorobenzoic acid

CAS: 82846-18-2

Formula: C₈H₇FO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 170.1378

Ref: IN-DA004SM1

4-Fluoro-3-methoxybenzoic acid

CAS: 82846-18-2

4-Fluoro-3-methoxybenzoic acid

Formula: C₈H₇FO₃

Purity: 96%

Color and Shape: white to off-white solid

Molecular weight: 170.14g/mol

Ref: 54-PC4823

4-Fluoro-3-methoxybenzoic Acid

CAS: 82846-18-2

Formula: C₈H₇FO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 170.14

Ref: 3B-F0681

4-Fluoro-3-methoxybenzoic acid

CAS: 82846-18-2

4-Fluoro-3-methoxybenzoic acid is a chiral, organic compound. It is an estrogen antagonist that binds to the estrogen receptor. 4-Fluoro-3-methoxybenzoic acid has been shown to inhibit tumor growth by blocking the interaction of estradiol with its receptor in the cancer cell line MCF-7. The metabolically active form of this compound is 4′-hydroxymethyl 4′,4″-difluorobenzoate and it can be converted into other metabolites such as 3′,4′,5′,6′-tetrahydroxybenzoic acid. This conversion may be mediated by cytochrome P450 enzymes or through hydrolysis by esterases or glucuronidases. The stereoisomers of 4-fluoro-3 methoxybenzoic acid are erythro and threo forms which have different affinities for

Formula: C₈H₇FO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 170.14 g/mol

Ref: 3D-FF66821

4-Fluoro-3-methoxybenzoic acid

CAS: 82846-18-2

Formula: C₈H₇FO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 170.139

Ref: 10-F005490