CAS 82854-37-3

Echinacoside

Description:

Echinacoside is a phenolic compound primarily derived from the Echinacea plant, particularly Echinacea purpurea. It is classified as a glycoside, consisting of a caffeic acid moiety linked to a glucose molecule. Echinacoside exhibits a range of biological activities, including antioxidant, anti-inflammatory, and immunomodulatory effects, which contribute to its use in traditional herbal medicine. The compound is known for its potential therapeutic properties, particularly in enhancing immune function and combating respiratory infections. Echinacoside is soluble in water and organic solvents, making it versatile for various applications in pharmaceuticals and nutraceuticals. Its stability and bioavailability are influenced by factors such as pH and temperature. Additionally, research continues to explore its mechanisms of action and potential benefits in health and wellness. As with many natural compounds, the efficacy and safety of echinacoside can vary based on dosage and individual health conditions, necessitating further studies to fully understand its therapeutic potential.

Formula: C₃₅H₄₆O₂₀

InChI: InChI=1/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1

InChI key: InChIKey=FSBUXLDOLNLABB-WZJPPVJYSA-N

SMILES: O(C(C=CC1=CC(O)=C(O)C=C1)=O)[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](OCCC4=CC(O)=C(O)C=C4)O[C@@H]2CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O

Synonyms:

• (2E)-3-(3,4-Dihydroxyphényl)acrylate de (2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphényl)éthoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}méthyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}tétrahydro-2H-pyran-3-yle
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl (2E)-3-(3,4-dihydroxyphenyl)acrylate
• (2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}tetrahydro-2H-pyran-3-yl-(2E)-3-(3,4-dihydroxyphenyl)acrylat
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]-beta-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside
• 6-Désoxy-alpha-L-mannopyranosyl-(1-> 3)-[bêta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphényl)-2-propènan-1-oyl]-bêta-D-glucopyranoside de 2-(3,4-dihydroxyphényl)éthyle
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]-
• beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-alpha-L-mannopyranosyl-(1-> 3)-O-[beta-D-glucopyranosyl-(1-> 6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→3)-O-[β-<smallcap>D</span>-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• Echinacoside
• β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]
• (1-3)-o-(beta-d-glucopyranosyl-(1-6))-,4-(3-(3,4-dihydroxyphenyl)-2-propenoat
• Echicoside
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)
• ECHINACOSIDE 20% DESERTLIVING CISTANCHE P.E.
• Echinacoside, froM Cistanche deserticola Y.C.Ma
• Echinacoside/CH54339
• [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)ethoxy]-5-hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• beta-d-e
• Cistanche tubulosa
• Echinacoside Standard
• ECHINACOSIDE(AHP)
• ECHINACOSIDE(AMERICAN HERBAL PHARMACOPOEIA)
• 2-(3,4-dihydroxyphenyl)ethylo-6-deoxy-alpha-l-mannopyranosyl-glucopyranosid
• Echinacoside, 98%, from Cistanche deserticola Y.C.Ma
• 2-(3,4-Dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-6-O-β-D-glucopyranosyl-4-O-[3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside
• Purpureaside C
• ECHINACOSIDE WITH HPLC

Echinacoside

CAS: 82854-37-3

Echinacoside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₃₅H₄₆O₂₀

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 786.74

Ref: 11-4988S

Echinacoside

CAS: 82854-37-3

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₃₅H₄₆O₂₀

Color and Shape: Off-White Powder

Molecular weight: 786.25824

Ref: 45-1231750

Echinacoside

CAS: 82854-37-3

Formula: C₃₅H₄₆O₂₀

Purity: %

Color and Shape: Solid

Molecular weight: 786.7277

Ref: IN-DA00G2TM

Echinacoside

CAS: 82854-37-3

Echinacoside

Purity: 98%

Molecular weight: 786.73g/mol

Ref: 54-OR1024253

Echinacoside

CAS: 82854-37-3

Echinacoside

Purity: ≥98%

Molecular weight: 786.73g/mol

Ref: 54-BUP00152

Echinacoside

CAS: 82854-37-3

Formula: C₃₅H₄₆O₂₀

Purity: ≥ 98.0%

Color and Shape: White off-white or beige powder

Molecular weight: 786.73

Ref: 7W-GL0233

Echinacoside

CAS: 82854-37-3

Echinacoside is a natural polyphenolic compound, has various kinds of pharmacological activities, such as anti-senescence, anti-hypoxia, anti-cancer, anti-osteoporosis, antioxidative, anti-inflammatory, neuroprotective, hepatoprotective, nitric oxide radical-scavenging and vasodilative ones. Echinacoside can improve the hematopoietic function of bone marrow in 5-FU-induced myelosuppression mice, it induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Echinacoside inhibits cytochrome c release and caspase-3 activation caused by ensuing rotenone exposure via activating Trk-extracellular signal-regulated kinase (ERK) pathway in neuronal cells.

Formula: C₃₅H₄₆O₂₀

Purity: 95%~99%

Molecular weight: 786.733

Ref: BP-BP0520

Echinacoside

CAS: 82854-37-3

Echinacoside: a polyphenol with anti-inflammatory, antioxidant, liver and nerve protection, NO scavenging, and vasodilation properties.

Formula: C₃₅H₄₆O₂₀

Purity: 99.59% - >99.99%

Color and Shape: White Crystal

Molecular weight: 786.73

Ref: TM-T1716

Echinacoside

CAS: 82854-37-3

Natural glycoside

Formula: C₃₅H₄₆O₂₀

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 786.74

Ref: 5G-89188

Echinacoside Ethanolate

CAS: 82854-37-3

Applications Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
References Gai, X. et al.: J. Pharm. Sci., 126, 155 (2014);

Formula: C₃₅H₄₆O₂₀

Color and Shape: Neat

Molecular weight: 786.73

Ref: TR-E325620

Echinacoside

CAS: 82854-37-3

Echinacoside is a caffeic acid derivative naturally found in plants, such as, Echinacea angustifolia DC. Echinacoside belongs to the class of phenylethanoid glycosides. In vitro studies have revealed the mode of action of echinacoside in breast cancer cells; echinacoside suppresses the Wnt/β-catenin signalling pathway exerting anticancer activity (Tang et al, 2020). Echinacoside has been reported as beneficial for human health in terms of neuroprotection, cardioprotectiony, anti-inflammatory, antioxidant and anti-osteoporotic activity (Liu, 2018).

Formula: C₃₅H₄₆O₂₀

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 786.74 g/mol

Ref: 3D-OE08287