CAS 82875-49-8

2-Chloro-5-(2,3-dihydro-3-oxo-1H-isoindol-1-yl)benzenesulfonamide

Description:

2-Chloro-5-(2,3-dihydro-3-oxo-1H-isoindol-1-yl)benzenesulfonamide, with the CAS number 82875-49-8, is a chemical compound characterized by its complex structure, which includes a chloro group, a sulfonamide moiety, and an isoindole derivative. This compound typically exhibits properties associated with sulfonamides, such as potential antibacterial activity, due to the presence of the sulfonamide functional group. The chloro substituent can influence its reactivity and solubility, while the isoindole structure may contribute to its biological activity. In terms of physical properties, it is likely to be a solid at room temperature, with moderate solubility in polar solvents. The compound may also exhibit specific spectral characteristics in techniques such as NMR and IR spectroscopy, which can be used for its identification and characterization. Overall, this compound's unique structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways.

Formula: C₁₄H₁₁ClN₂O₃S

InChI: InChI=1S/C14H11ClN2O3S/c15-11-6-5-8(7-12(11)21(16,19)20)13-9-3-1-2-4-10(9)14(18)17-13/h1-7,13H,(H,17,18)(H2,16,19,20)

InChI key: InChIKey=NPCMXXHTULKTQS-UHFFFAOYSA-N

SMILES: O=C1NC(C=2C1=CC=CC2)C3=CC(S(N)(=O)=O)=C(Cl)C=C3

Synonyms:

• 2-Chloro-5-(3-oxo-1,2-dihydroisoindol-1-yl)benzenesulfonamide
• Benzenesulfonamide, 2-chloro-5-(2,3-dihydro-3-oxo-1H-isoindol-1-yl)-
• 3-(3-Sulfamyl-4-chlorophenyl)phthalimidine
• 2-Chloro-5-(2,3-dihydro-3-oxo-1H-isoindol-1-yl)benzenesulfonamide

Deoxy Chlorthalidone (2-Chloro-5-(3-oxoisoindolin-1-yl)benzenesulfonamide)

CAS: 82875-49-8

Sulfonamides, nesoi

Formula: C₁₄H₁₁ClN₂O₃S

Color and Shape: White Powder

Molecular weight: 322.01789

Ref: 45-1A11020

Chlortalidone (Chlorthalidone) EP Impurity E

CAS: 82875-49-8

Formula: C₁₄H₁₁ClN₂O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 322.76

Ref: 4Z-C-140005

Chlortalidone EP Impurity E

CAS: 82875-49-8

Formula: C₁₄H₁₁ClN₂O₃S

Molecular weight: 322.76

Ref: ST-EA-CP-C20005

3-Dehydroxy Chlorthalidone

Controlled Product

CAS: 82875-49-8

Formula: C₁₄H₁₁ClN₂O₃S

Color and Shape: Neat

Molecular weight: 322.77

Ref: TR-D230540

3-Dehydroxy Chlorthalidone-d4

Controlled Product

CAS: 82875-49-8

Applications 3-Dehydroxy Chlorthalidone-d4 is the isotope labelled analog of 3-Dehydroxy Chlorthalidone (D230540), which is an metabolite of Chlorthalidone (C427500), a diuretic and antihypertensive agent.
References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),

Formula: C₁₄D₄H₇ClN₂O₃S

Color and Shape: Neat

Molecular weight: 326.791

Ref: TR-D230542

Chlorthalidone impurity E

CAS: 82875-49-8

Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>

Formula: C₁₄H₁₁ClN₂O₃S

Purity: Min. 95%

Molecular weight: 322.77 g/mol

Ref: 3D-IC76330