CAS 83-43-2

Methylprednisolone

Description:

Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various conditions such as allergies, autoimmune diseases, and certain types of cancer. It is characterized by its chemical formula C22H30O5 and a molecular weight of approximately 374.48 g/mol. Methylprednisolone acts by modulating the immune response and inhibiting the release of inflammatory mediators. It is typically administered in oral, injectable, or topical forms, depending on the condition being treated. The substance is known for its relatively rapid onset of action and can be used in both acute and chronic settings. Side effects may include weight gain, mood changes, and increased susceptibility to infections, particularly with long-term use. Methylprednisolone is classified under the glucocorticoid category of steroids and is often prescribed in a tapering regimen to minimize withdrawal symptoms. Its efficacy and safety profile make it a valuable medication in clinical practice, although careful monitoring is essential to mitigate potential adverse effects.

Formula: C₂₂H₃₀O₅

InChI: InChI=1/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14?,15?,17-,19?,20-,21-,22-/m0/s1

InChI key: InChIKey=VHRSUDSXCMQTMA-PJHHCJLFSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](C)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]

Synonyms:

• (6Alpha,11Beta)-11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
• (6Alpha,8Xi,9Xi,11Beta,14Xi)-11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
• (6α,11β)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
• 11,17,21-Trihydroxy-6-Methylpregna-1,4-Diene-3,20-Dione
• 11-Beta,17-Alpha,21-Trihydroxy-6-Alpha-Methylpregna-1,4-Diene-3,20-Dione
• 11β,17,21-Trihydroxy-6α-methylpregna-1,4-diene-3,20-dione
• 11β,17α,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione
• 6-α-Methylprednisolone
• 6alpha-Methyl Prednisolone
• 6α-Methyl-11β,17α,21β-trihydroxy-1,4-pregnadiene-3,20-dione
• 6α-Methylprednisolone
• A-Methapred
• Besonia
• Dopomedrol
• Duralone
• M-Prednisol
• Medesone
• Medorol
• Medralone
• Medrate
• Medrol
• Medrone
• Metastab
• Methyl prednisolone
• Methylprednisolon
• Methylprednisolone
• Methypred
• Metilbetasone
• Metilprednisolona
• Metilprednisolone
• Metipred
• Metrisone
• Moderin
• Noretona
• Nsc 19987
• Prednol
• Prednol L
• Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6α,11β)-
• Pregna-1,4-diene-3,20-dione, 11β,17,21-trihydroxy-6α-methyl-
• Promacortine
• Solimedrol
• Suprametil
• Sw 196788
• U 7532
• Urbason
• Urbasone
• Urbazone
• Wyacort
• Δ1-6α-Methylhydrocortisone
• Δ¹-6α-Methylhydrocortisone
• 6A-METHYLPREDNISOLINE
• 6-ALFA-METHYLPREDNISOLONE
• 6-ALPHA-METHYLPREDNISOLONE
• 6 ALPHA-METHYLPREDNISOLONE BASE
• 11b,17a,21-trihydroxy-6a-methyl-1,4-pregnene-3,20-dione
• 6-ALPHA-METHYL-11BETA, 17D,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE
• 11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
• 6ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE
• 1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE
• 11,17,21-trihydroxy-6-methyl-1,4-pregnadiene-3,20-dione
• 6alpha-methyl-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione
• 1-dehydro-6alpha-methylhydrocortisone
• METHYLRPEDNISOLINE

6α-Methylprednisolone-13C3

Controlled Product

CAS: 83-43-2

Formula: C₃C₁₉H₃₀O₅

Color and Shape: Neat

Molecular weight: 377.449

Ref: TR-M325991

(11,12,12,6α-Methyl-D6)-Prednisolone

Controlled Product

CAS: 83-43-2

Applications (11,12,12,6α-Methyl-D6)-Prednisolone is the labeled analogue of 6α-Methyl Prednisolone (M325934), a glucocorticoid which displays anti-inflamatory and antioxidant properties and attenuates apoptosis in oligodendrocytes after injury. 6α-Methyl Prednisolone is neuroprotective.
References Hall, E.D., et al.: J. Neurosurg., 76, 13 (1992); Hommes, O.R., et al.: Mult. Scler., 1, 327 (1996); Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998); Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999)

Formula: C₂₂D₆H₂₄O₅

Color and Shape: Neat

Molecular weight: 380.508

Ref: TR-M327232

Metilprednisolone

CAS: 83-43-2

Formula: C₂₂H₃₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 374.4706

Ref: IN-DA003AXD