CAS 83-98-7

(±)-Orphenadrine

Description:

(±)-Orphenadrine is a synthetic compound primarily used as an anticholinergic agent and muscle relaxant. It is classified as a tertiary amine and is structurally related to diphenhydramine, featuring a phenyl group and a piperidine ring. The substance exhibits a racemic mixture, meaning it contains equal parts of two enantiomers, which can influence its pharmacological effects. Orphenadrine acts by blocking the action of acetylcholine at muscarinic receptors, leading to reduced muscle spasms and pain relief. It is commonly utilized in the treatment of muscle pain and discomfort, often in conjunction with physical therapy. The compound is typically administered orally or via intramuscular injection. In terms of physical properties, orphenadrine is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. As with many medications, it may have side effects, including dry mouth, dizziness, and sedation, and should be used with caution in patients with certain medical conditions.

Formula: C₁₈H₂₃NO

InChI: InChI=1S/C18H23NO/c1-15-9-7-8-12-17(15)18(20-14-13-19(2)3)16-10-5-4-6-11-16/h4-12,18H,13-14H2,1-3H3

InChI key: InChIKey=QVYRGXJJSLMXQH-UHFFFAOYSA-N

SMILES: C(OCCN(C)C)(C1=C(C)C=CC=C1)C2=CC=CC=C2

Synonyms:

• (.+-.)-Orphenadrine
• 2-Methyldiphenhydramine
• Biorphen
• Brocadisipal
• Bs 5930
• Ethylamine, N,N-dimethyl-2-[(o-methyl-α-phenylbenzyl)oxy]-
• N,N-Dimethyl-2-(o-methyl-α-phenylbenzyloxy)ethylamine
• N,N-Dimethyl-2-[(2-methylphenyl)phenylmethoxy]ethanamine
• N,N-Dimethyl-N-[2-(o-methyl-α-phenylbenzyloxy)ethyl]amine
• ORP
• Orfenadrina
• Orphenadine
• Orphenadrin
• Phenyl-o-tolylmethyl dimethylaminoethyl ether
• Ws 2434
• o-Methyldiphenhydramine

Orphenadrine

CAS: 83-98-7

Orphenadrine

Purity: ≥98%

Molecular weight: 269.38g/mol

Ref: 54-BUP10461

Orphenadrine-d3

CAS: 83-98-7

Formula: C₁₈H₂₀D₃NO

Molecular weight: 272.41

Ref: 4Z-O-051

Orphenadrine

CAS: 83-98-7

Formula: C₁₈H₂₃NO

Molecular weight: 269.39

Ref: 4Z-O-052

Orphenadrine-d4

CAS: 83-98-7

Formula: C₁₈H₁₉NOD₄

Molecular weight: 273.41

Ref: 4Z-O-054

Orphenadrine

CAS: 83-98-7

Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,

Formula: C₁₈H₂₃NO

Purity: 98.91% - 99.11%

Color and Shape: Solid

Molecular weight: 269.38

Ref: TM-T68599