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CAS 83159-91-5

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3,5-Di-O-(tert-butyldimethylsilyl)-2-deoxy-D-ribonolactone

Description:
3,5-Di-O-(tert-butyldimethylsilyl)-2-deoxy-D-ribonolactone is a chemical compound that belongs to the class of silyl ethers, which are often used in organic synthesis and as protecting groups for hydroxyl functionalities. This compound features a lactone structure, indicating the presence of a cyclic ester, which is derived from the condensation of a hydroxy acid. The tert-butyldimethylsilyl (TBDMS) groups serve to protect the hydroxyl groups at the 3 and 5 positions of the ribonolactone, enhancing the compound's stability and reactivity during synthetic procedures. The presence of the 2-deoxy configuration indicates that it is a derivative of ribonucleic acid (RNA), lacking an oxygen atom at the 2-position of the ribose sugar. This modification is significant in biochemical applications, particularly in the synthesis of nucleoside analogs and other derivatives used in medicinal chemistry. The compound is typically characterized by its solubility in organic solvents and its stability under standard laboratory conditions, making it a valuable intermediate in synthetic organic chemistry.
Formula:C17H36O4Si2
Synonyms:
  • 3,5-Di-O-(tert-Butyldimethylsilyl)-2-deoxy-D-ribono-1,4-lactone
  • 3,5-Di-O-(tert-butyldimethylsilyl)-2-deoxy-D-ribose
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