CymitQuimica logo

CAS 83366-66-9

:

Nefazodone

Description:
Nefazodone is an antidepressant medication primarily used to treat major depressive disorder. It belongs to the class of drugs known as serotonin antagonist and reuptake inhibitors (SARIs). Nefazodone functions by modulating serotonin levels in the brain, which helps improve mood and alleviate depressive symptoms. The chemical formula for nefazodone is C17H18ClN3O2S, and it features a complex structure that includes a phenylpiperazine moiety and a thienyl group. It is typically administered in oral form and is known for its relatively favorable side effect profile compared to other antidepressants, although it can still cause drowsiness, dizziness, and gastrointestinal disturbances. Importantly, nefazodone has been associated with rare but serious liver toxicity, necessitating monitoring of liver function during treatment. The drug is metabolized primarily in the liver, and its pharmacokinetics can be influenced by various factors, including other medications and individual patient characteristics. Overall, nefazodone represents a unique option in the pharmacological management of depression.
Formula:C25H32ClN5O2
InChI:InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3
InChI key:InChIKey=VRBKIVRKKCLPHA-UHFFFAOYSA-N
SMILES:C(COC1=CC=CC=C1)N2C(CC)=NN(CCCN3CCN(CC3)C4=CC(Cl)=CC=C4)C2=O
Synonyms:
  • 2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one
  • Nefazodone
  • 3H-1,2,4-Triazol-3-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.