CAS 834-28-6: phenformin hydrochloride
Description:Phenformin hydrochloride is a pharmaceutical compound primarily used as an antidiabetic agent, belonging to the biguanide class of medications. It is characterized by its ability to lower blood glucose levels by enhancing insulin sensitivity and reducing hepatic glucose production. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Its chemical structure includes a phenyl group, which contributes to its pharmacological properties. Phenformin hydrochloride has been associated with gastrointestinal side effects and, in some cases, lactic acidosis, leading to its withdrawal from the market in many countries. Despite its historical use, it is important to note that its safety profile has raised concerns, prompting the development of alternative medications with improved safety and efficacy. As with any pharmaceutical agent, proper dosage and monitoring are essential to minimize risks and maximize therapeutic benefits.
Formula:C10H15N5·ClH
InChI:InChI=1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
InChI key:InChIKey=YSUCWSWKRIOILX-UHFFFAOYSA-N
SMILES:Cl.N=C(N)NC(=N)NCCC=1C=CC=CC1
- Synonyms:
- 1-(2-Phenylethyl)biguanide hydrochloride
- 1-(Diaminomethylidene)-2-(2-Phenylethyl)Guanidine Hydrochloride (1:1)
- 1-Phenethylbiguanide hydrochloride
- 1-β-Phenylethylbiguanide hydrochloride
- Azucaps
- Biguanide, 1-phenethyl-, monohydrochloride
- Dbi-Td
- Debeone DT
- Debinyl
- Dibein
- See more synonyms
- Dipar
- Feguanide
- Glucopostin
- Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1)
- Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
- Insoral
- Lentobetic
- Meltrol
- N-Phenethylbiguanide hydrochloride
- Normoglucina
- N′-β-Phenylethylbiguanide-hydrochloride
- Phenethylbiguanide hydrochloride
- Phenformin Hcl
- Phenformine HCL
- α-Phenethylbiguanide hydrochloride