CAS 834-28-6

phenformin hydrochloride

Description:

Phenformin hydrochloride is a pharmaceutical compound primarily used as an antidiabetic agent, belonging to the biguanide class of medications. It is characterized by its ability to lower blood glucose levels by enhancing insulin sensitivity and reducing hepatic glucose production. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Its chemical structure includes a phenyl group, which contributes to its pharmacological properties. Phenformin hydrochloride has been associated with gastrointestinal side effects and, in some cases, lactic acidosis, leading to its withdrawal from the market in many countries. Despite its historical use, it is important to note that its safety profile has raised concerns, prompting the development of alternative medications with improved safety and efficacy. As with any pharmaceutical agent, proper dosage and monitoring are essential to minimize risks and maximize therapeutic benefits.

Formula: C₁₀H₁₆ClN₅

InChI: InChI=1/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H

InChI key: InChIKey=YSUCWSWKRIOILX-UHFFFAOYSA-N

SMILES: C(CNC(NC(=N)N)=N)C1=CC=CC=C1.Cl

Synonyms:

• 1-(2-Phenylethyl)biguanide hydrochloride
• 1-(Diaminomethylidene)-2-(2-Phenylethyl)Guanidine Hydrochloride (1:1)
• 1-Phenethylbiguanide hydrochloride
• 1-β-Phenylethylbiguanide hydrochloride
• Azucaps
• Biguanide, 1-phenethyl-, monohydrochloride
• Dbi-Td
• Debeone DT
• Debinyl
• Dibein
• Dipar
• Feguanide
• Glucopostin
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
• Insoral
• Lentobetic
• Meltrol
• N-Phenethylbiguanide hydrochloride
• Normoglucina
• N′-β-Phenylethylbiguanide-hydrochloride
• Phenethylbiguanide hydrochloride
• Phenformin Hcl
• Phenformine HCL
• α-Phenethylbiguanide hydrochloride
• n-beta-phenylethylbiguanidehydrochloride
• 1-fenetilbiguanidecloridrato
• n’-beta-phenethylbiguanidehydrochloride
• 1-phenethyl-biguanidhydrochloride
• phenoforminehydrochloride
• phenforminhclno.9113
• PHENFORMIN HYDROCHLORIDE
• n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
• usafvi-6
• 1-phenethyl-biguanidmonohydrochloride
• PHENFORMINI HYDROCHLORIDE
• Insora
• 1-phenylaethylbiguanidhydrochlorid

Phenformin Hydrochloride

CAS: 834-28-6

Color and Shape: Neat

Ref: 61-FOR1574.00

Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 241.7205

Ref: IN-DA00IDAP

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.

Formula: C₁₀H₁₆ClN₅

Purity: 97.11% - 99.80%

Color and Shape: Lactic Acidosis

Molecular weight: 241.72

Ref: TM-T1453

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride

Purity: ≥95%

Molecular weight: 241.72g/mol

Ref: 54-BUP19681

Phenformin Hydrochloride

CAS: 834-28-6

Phenformin Hydrochloride

Purity: 97%

Molecular weight: 241.72g/mol

Ref: 54-OR1014623

Phenformin HCl

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 205.27 36.46

Ref: 4Z-P-751

Phenformin Hydrochloride

Controlled Product

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·ClH

Color and Shape: Neat

Molecular weight: 241.72

Ref: 86-MM1574.00

Phenformin hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₅N₅·ClH

Color and Shape: Neat

Molecular weight: 241.72

Ref: 04-C16004500

Phenformin-d5 Hydrochloride

Controlled Product

CAS: 834-28-6

Applications Isotope labelled Phenformin It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Formula: C₁₀D₅H₁₀N₅·ClH

Color and Shape: Neat

Molecular weight: 210.29+36.46x

Ref: TR-P296902

Phenformin Hydrochloride

CAS: 834-28-6

Applications It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),

Formula: C₁₀H₁₅N₅·ClH

Color and Shape: Neat

Molecular weight: 241.72

Ref: TR-P296900

N-(2-phenylethyl)imidodicarbonimidic diamide hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₆ClN₅

Purity: ≥97%

Color and Shape: Solid

Molecular weight: 241.72

Ref: 10-F375298

Phenformin Hydrochloride

CAS: 834-28-6

Formula: C₁₀H₁₅N₅HCl

Molecular weight: 205.27 : 36.46

Ref: ST-EA-CP-P236000

Phenformin hydrochloride

CAS: 834-28-6

Phenformin hydrochloride is a phenformin derivative that is used as an oral hypoglycemic. It has been shown to inhibit the synthesis of fatty acids in the liver and to reduce the size of lipid droplets, which are a hallmark of hepatic steatosis. Phenformin hydrochloride also inhibits the polymerase chain reaction and mitochondrial membrane potential, which results in reduced oxidative stress and apoptosis. This drug has been shown to have anti-infectious effects against infectious diseases such as typhoid fever, tuberculosis, and malaria. Phenformin hydrochloride may also be carcinogenic, due to its ability to induce skin cancer in mice with a genetic predisposition for this type of cancer. The drug should not be administered to patients with metabolic disorders or patients who are receiving chemotherapy agents that affect cell proliferation because it can exacerbate these conditions.

Formula: C₁₀H₁₆ClN₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 241.72 g/mol

Ref: 3D-FP26876