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CAS 83409-32-9

:

Desethylamiodarone

Description:
Desethylamiodarone is a chemical compound that is a derivative of amiodarone, a well-known antiarrhythmic medication. It is characterized by its complex structure, which includes a benzofuran moiety and an iodine atom, although desethylamiodarone has one less ethyl group compared to amiodarone. This compound exhibits significant pharmacological activity, primarily as an antiarrhythmic agent, and is known for its ability to prolong the action potential duration in cardiac tissues. Desethylamiodarone is lipophilic, which contributes to its distribution in body tissues and its long half-life. It is also associated with various side effects, including potential thyroid dysfunction due to its iodine content. The compound is typically studied in the context of cardiovascular pharmacology and is of interest for its therapeutic potential as well as its metabolic pathways, particularly how it is formed from the metabolism of amiodarone in the body. Its CAS number, 83409-32-9, is used for identification in chemical databases and regulatory contexts.
Formula:C23H25I2NO3
InChI:InChI=1S/C23H25I2NO3/c1-3-5-9-20-21(16-8-6-7-10-19(16)29-20)22(27)15-13-17(24)23(18(25)14-15)28-12-11-26-4-2/h6-8,10,13-14,26H,3-5,9,11-12H2,1-2H3
InChI key:InChIKey=VXOKDLACQICQFA-UHFFFAOYSA-N
SMILES:C(=O)(C=1C=2C(OC1CCCC)=CC=CC2)C3=CC(I)=C(OCCNCC)C(I)=C3
Synonyms:
  • (2-Butyl-1-benzofuran-3-yl)-[4-(2-ethylaminoethoxy)-3,5-diiodophenyl]methanone
  • (2-Butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]methanone
  • Desethylamiodarone
  • (2-butyl-1-benzofuran-3-yl){4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl}methanone
  • N-Desethylamiodarone
  • N-Monodesethylamiodarone
  • Methanone, (2-butyl-3-benzofuranyl)[4-[2-(ethylamino)ethoxy]-3,5-diiodophenyl]-
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