CAS 83420-94-4

N,N-diprop-2-en-1-yl-L-tyrosyl-N-(2-{[(1S)-1-benzyl-2-{[(1S)-1-carboxy-3-methylbutyl]amino}-2-oxoethyl]sulfanyl}ethyl)glycinamide

Description:

N,N-diprop-2-en-1-yl-L-tyrosyl-N-(2-{[(1S)-1-benzyl-2-{[(1S)-1-carboxy-3-methylbutyl]amino}-2-oxoethyl]sulfanyl}ethyl)glycinamide, with CAS number 83420-94-4, is a complex organic compound characterized by its intricate structure, which includes multiple functional groups such as amides, sulfides, and alkenes. This compound features a dipropenyl group, indicating the presence of two propene units, which contributes to its reactivity and potential applications in organic synthesis. The presence of the L-tyrosyl and glycinamide moieties suggests that it may exhibit biological activity, possibly interacting with specific receptors or enzymes due to the amino acid components. The stereochemistry indicated by the (1S) notation implies specific spatial arrangements that can influence the compound's pharmacological properties. Overall, this substance is likely to be of interest in medicinal chemistry and biochemistry, particularly in the development of novel therapeutic agents or as a research tool in studying protein interactions and enzyme mechanisms.

Formula: C₃₄H₄₆N₄O₆S

InChI: InChI=1/C34H46N4O6S/c1-5-17-38(18-6-2)29(21-26-12-14-27(39)15-13-26)32(41)36-23-31(40)35-16-19-45-30(22-25-10-8-7-9-11-25)33(42)37-28(34(43)44)20-24(3)4/h5-15,24,28-30,39H,1-2,16-23H2,3-4H3,(H,35,40)(H,36,41)(H,37,42)(H,43,44)/t28-,29-,30-/m0/s1

SMILES: C=CCN(CC=C)[C@@H](Cc1ccc(cc1)O)C(=NCC(=NCCS[C@@H](Cc1ccccc1)C(=N[C@@H](CC(C)C)C(=O)O)O)O)O

ICI 154129

CAS: 83420-94-4

ICI 154129 is a potent and selective δ-opioid receptor antagonist. It has been shown to produce antinociceptive effects in animal models of pain, and ICI 154129 has been shown to have an addictive potential in animals. ICI 154129 binds to the δ-opioid receptor with high affinity and selectivity, with a K i of 0.5 nM. It also binds to other opioid receptors at higher concentrations, including β-opioid receptors (K i = 1.3 nM) and μ-opioid receptors (K i = 2.6 nM). ICI 154129 is a competitive antagonist at all three opioid receptors, preventing binding of endogenous or exogenous agonists or antagonists. There are very few side effects associated with this drug, which may be due to its low affinity for other targets such as dopamine or serotonin receptors.

Formula: C₃₄H₄₆N₄O₆S

Purity: Min. 95%

Molecular weight: 638.8 g/mol

Ref: 3D-IDA42094

ICI 154,129

CAS: 83420-94-4

Selective δ opioid antagonist

Formula: C₃₄H₄₆N₄O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 638.82

Ref: TM-T22847