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CAS 83435-67-0

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Delapril hydrochloride

Description:
Delapril hydrochloride is an antihypertensive medication primarily used to manage high blood pressure. It belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors, which work by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a potent vasoconstrictor. This action leads to vasodilation, reduced blood pressure, and decreased workload on the heart. Delapril is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. The compound is characterized by its ability to improve cardiovascular outcomes and is often prescribed in conjunction with other antihypertensive agents for better efficacy. Common side effects may include cough, elevated potassium levels, and hypotension. As with other ACE inhibitors, caution is advised in patients with renal impairment or those who are pregnant. Overall, Delapril hydrochloride is a valuable therapeutic option in the management of hypertension and related cardiovascular conditions.
Formula:C26H32N2O5·ClH
InChI:InChI=1S/C26H32N2O5.ClH/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22;/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30);1H/t18-,23-;/m0./s1
InChI key:InChIKey=FDJCVHVKXFIEPJ-JCNFZFLDSA-N
SMILES:N(C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)=O)(CC(O)=O)C2CC=3C(C2)=CC=CC3.Cl
Synonyms:
  • Adecut
  • Ccris 1925
  • Cupressin
  • Cv 3317
  • Delapril HCl
  • Delapril hydrochloride [USAN:JAN]
  • Ethyl (S)-2-(((S)-1-((carboxymethyl)-2-indanylcarbamoyl)ethyl)amino)-4-phenylbutyrate, monohydrochloride
  • Glycine, N-((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl-N-(2,3-dihydro-1H-inden-2-yl)-, monohydrochloride
  • Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-, monohydrochloride, (S)-
  • Glycine, N-(2,3-dihydro-1H-inden-2-yl)-N-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-<span class="text-smallcaps">L</span>-alanyl]-, monohydrochloride, (S)-
  • See more synonyms
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Found 7 products.