CAS 835-31-4

Naphazoline

Description:

Naphazoline is a sympathomimetic agent primarily used as a topical decongestant in nasal sprays and eye drops. It belongs to the imidazoline class of compounds and acts primarily as an alpha-adrenergic agonist, leading to vasoconstriction and reduced swelling in mucous membranes. Naphazoline is characterized by its rapid onset of action and relatively short duration of effect, making it effective for temporary relief of nasal congestion and redness in the eyes. The compound is typically administered in low concentrations due to its potency and potential side effects, which can include rebound congestion, irritation, and increased blood pressure with prolonged use. Naphazoline is generally well-tolerated when used as directed, but caution is advised in patients with cardiovascular conditions or those taking monoamine oxidase inhibitors. Its chemical structure features a naphthalene ring, contributing to its lipophilicity, which aids in its absorption and efficacy in target tissues.

Formula: C₁₄H₁₄N₂

InChI: InChI=1S/C14H14N2/c1-2-7-13-11(4-1)5-3-6-12(13)10-14-15-8-9-16-14/h1-7H,8-10H2,(H,15,16)

InChI key: InChIKey=CNIIGCLFLJGOGP-UHFFFAOYSA-N

SMILES: C(C=1C2=C(C=CC1)C=CC=C2)C=3NCCN3

Synonyms:

• 1H-Imidazole, 4,5-dihydro-2-(1-naphthalenylmethyl)-
• 2-(1-Naphthalenylmethyl)-2-imidazoline
• 2-(1-Naphthylmethyl)-2-Imidazoline
• 2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
• 2-Imidazoline, 2-(1-naphthylmethyl)-
• 2-[(Naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole
• 4,5-Dihydro-2-(1-naphthalenylmethyl)-1H-imidazole
• Antan
• Antigaimorit
• Colirio Alfa
• Euboral Oftalmico
• Imidin
• Nafazoline
• Naphconforte
• Naphthazoline
• Naphthizine
• Nephazoline
• Niazol
• Rhinazine

2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole

CAS: 835-31-4

Formula: C₁₄H₁₄N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 210.2744

Ref: IN-DA00G27Z

Naphazoline

CAS: 835-31-4

Naphazoline

Purity: ≥98%

Molecular weight: 210.27g/mol

Ref: 54-BUP06580

Naphazoline

CAS: 835-31-4

Formula: C₁₄H₁₄N₂

Color and Shape: White To Off-White Solid

Molecular weight: 210.28

Ref: 4Z-N-331

Nadaplatin

CAS: 835-31-4

Ref: 7W-GP3812

Naphazoline

CAS: 835-31-4

Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.

Formula: C₁₄H₁₄N₂

Purity: 99.79%

Color and Shape: White Crystalline Powder Solid

Molecular weight: 210.27

Ref: TM-T21445