CAS 83546-42-3

2'-Fluoro-5-ethylarabinosyluracil

Description:

2'-Fluoro-5-ethylarabinosyluracil, with the CAS number 83546-42-3, is a nucleoside analog that features a fluorine atom at the 2' position and an ethyl group at the 5-position of the uracil base. This compound is characterized by its structural modifications that enhance its stability and bioactivity compared to natural nucleosides. The presence of the fluorine atom can influence the compound's interaction with nucleic acid targets, potentially affecting its antiviral or anticancer properties. The ethyl group contributes to the lipophilicity of the molecule, which may enhance its cellular uptake. As a nucleoside analog, it may interfere with nucleic acid synthesis and function, making it a subject of interest in medicinal chemistry and drug development. Its unique structural features may also lead to specific biological activities, making it a candidate for further research in therapeutic applications. Overall, 2'-Fluoro-5-ethylarabinosyluracil represents a significant modification of natural nucleosides with potential implications in pharmacology.

Formula: C₁₁H₁₅FN₂O₅

InChI: InChI=1/C11H15FN2O5/c1-2-5-3-14(11(18)13-9(5)17)10-7(12)8(16)6(4-15)19-10/h3,6-8,10,15-16H,2,4H2,1H3,(H,13,17,18)/t6-,7+,8-,10-/m1/s1

Synonyms:

• 2'-Fluoro-5-ethyl-beta-D-arabinofuranosyluracil
• 5-Ethyl-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethylpyrimidine-2,4(1H,3H)-dione

2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine

CAS: 83546-42-3

2'-Deoxy-2'-fluoro-5-ethyl-arabinouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, Arabino-nucleoside, 5-Modified pyrimidine nucleoside, 2'-

Formula: C₁₁H₁₅FN₂O₅

Color and Shape: Solid

Molecular weight: 274.25

Ref: TM-TNU0190

1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil

CAS: 83546-42-3

1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)-5-ethyluracil is a nucleoside analog with modifications to alter its biological activity. It contains a β-D-arabinofuranose sugar instead of the standard β-D-deoxyribose in natural nucleosides and
the fluorine (F) at the 2'-position increases resistance to enzymatic degradation and alters its biological activity. The 5-ethyl modification on the uracil ring enhances its interaction with viral polymerases.

Formula: C₁₁H₁₅FN₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 274.25 g/mol

Ref: 3D-ND05411