CAS 835621-07-3

2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)

Description:

2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1) is a complex organic compound characterized by its multi-functional structure, which includes a pyridine ring, amide groups, and a chloro-trifluoromethyl phenyl moiety. This compound is typically classified as a pharmaceutical intermediate or active ingredient, often investigated for its potential biological activities, including anti-inflammatory or anticancer properties. The presence of halogen substituents, such as chlorine and fluorine, can enhance lipophilicity and influence the compound's pharmacokinetic properties. As a hydrochloride salt, it is likely to exhibit improved solubility in aqueous environments, facilitating its use in biological assays or formulations. The compound's molecular interactions, stability, and reactivity are influenced by its functional groups, making it a subject of interest in medicinal chemistry. Safety data and handling precautions are essential due to the presence of halogenated components, which may pose environmental and health risks.

Formula: C₂₁H₁₅ClF₄N₄O₃·ClH

InChI: InChI=1S/C21H15ClF4N4O3.ClH/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26;/h2-10H,1H3,(H,27,31)(H2,29,30,32);1H

InChI key: InChIKey=ACSWJKPZXNIVMY-UHFFFAOYSA-N

SMILES: O(C=1C=C(C(NC)=O)N=CC1)C2=CC(F)=C(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=O)C=C2.Cl

Synonyms:

• 2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, hydrochloride (1:1)
• 2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-, monohydrochloride
• Regafenib hydrochloride

Regorafenib (Hydrochloride)

CAS: 835621-07-3

Formula: C₂₁H₁₆Cl₂F₄N₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 519.2764

Ref: IN-DA00G3PQ

4-(4-(3-(4-Chloro-3-(Trifluoromethyl)Phenyl)Ureido)-3-Fluorophenoxy)-N-Methylpicolinamide Hydrochloride

CAS: 835621-07-3

4-(4-(3-(4-Chloro-3-(Trifluoromethyl)Phenyl)Ureido)-3-Fluorophenoxy)-N-Methylpicolinamide Hydrochloride

Purity: 98%

Molecular weight: 519.28g/mol

Ref: 54-PC109065

Regorafenib Hydrochloride

CAS: 835621-07-3

Regorafenib Hydrochloride

Purity: ≥98%

Molecular weight: 519.28g/mol

Ref: 54-BUP13589

Regorafenib Hydrochloride

CAS: 835621-07-3

Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.

Formula: C₂₁H₁₆Cl₂F₄N₄O₃

Purity: 99.56%

Color and Shape: Solid

Molecular weight: 519.28

Ref: TM-T8402