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CAS 83643-84-9

:

methyl trifluoroacetoacetate

Description:
Methyl trifluoroacetoacetate is an organic compound characterized by its trifluoromethyl and acetoacetate functional groups. It typically appears as a colorless to pale yellow liquid with a distinctive odor. This compound is known for its high reactivity, particularly in nucleophilic substitution reactions, due to the presence of the trifluoromethyl group, which enhances electrophilicity. Methyl trifluoroacetoacetate is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. It is often utilized in synthetic organic chemistry, particularly in the synthesis of fluorinated compounds and as an intermediate in the production of pharmaceuticals and agrochemicals. The trifluoromethyl group imparts unique properties, including increased lipophilicity and metabolic stability, making it valuable in drug design. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate protective equipment should be used.
Formula:C5H5F3O3
Synonyms:
  • Methyl 4,4,4-trifluoro-3-oxobutanoate
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