CAS 83851-38-1

leukotriene A3 methyl ester

Description:

Leukotriene A3 methyl ester is a synthetic derivative of leukotriene A3, a type of eicosanoid that plays a significant role in inflammatory responses and immune system regulation. This compound is characterized by its structure, which includes a methyl ester functional group, enhancing its stability and solubility compared to its parent compound. Leukotriene A3 methyl ester is known for its biological activity, particularly in mediating bronchoconstriction and influencing various cellular processes, including chemotaxis and vascular permeability. It is often studied in the context of asthma and allergic reactions due to its potent effects on smooth muscle contraction and inflammation. The compound is typically used in research settings to explore the mechanisms of leukotriene action and its potential therapeutic implications. As with many eicosanoids, its activity is tightly regulated in biological systems, and its synthesis and degradation are crucial for maintaining homeostasis. Safety and handling precautions are essential when working with this compound, as it can elicit strong biological responses.

Formula: C₂₁H₃₄O₃

InChI: InChI=1/C21H34O3/c1-3-4-5-6-7-8-9-10-11-12-13-14-16-19-20(24-19)17-15-18-21(22)23-2/h10-14,16,19-20H,3-9,15,17-18H2,1-2H3/b11-10-,13-12+,16-14+/t19-,20-/m0/s1

Leukotriene A3 methyl ester

CAS: 83851-38-1

Formula: C₂₁H₃₄O₃

Molecular weight: 334.49

Ref: 7W-GL7401

Leukotriene A3 methyl ester

CAS: 83851-38-1

Leukotriene A3 methyl ester is a medicinal analog that has been identified in human urine and shown to have potent anticancer properties. It acts as a protein kinase inhibitor, inhibiting the activity of kinases involved in cancer cell growth and survival. Leukotriene A3 methyl ester has been found to induce apoptosis (cell death) in tumor cells and may be useful in developing new cancer therapies. Studies have also shown that this compound has inhibitory effects on Chinese hamster ovary cells, making it a promising candidate for further research into its potential as an anticancer agent.

Formula: C₂₁H₃₄O₃

Purity: Min. 95%

Molecular weight: 334.5 g/mol

Ref: 3D-IDA85138

Leukotriene A3 methyl ester

CAS: 83851-38-1

LTA3, made from 5,8,11-eicosatrienoic acid via 5-LO, is unstable; its stable methyl ester form turns into free acid when needed.

Formula: C₂₁H₃₄O₃

Color and Shape: Solid

Molecular weight: 334.49

Ref: TM-T37615