Colony-stimulating factor 2 (CSF2), also known as granulocyte-macrophage colony-stimulating factor (GM-CSF), is a glycoprotein that plays a crucial role in hematopoiesis, particularly in the differentiation and proliferation of myeloid progenitor cells into granulocytes and macrophages. It is produced by various cell types, including T cells, macrophages, and endothelial cells, in response to inflammatory stimuli. CSF2 functions by binding to its specific receptor, which activates signaling pathways that promote cell survival, proliferation, and differentiation. The substance is characterized by its ability to enhance the immune response, making it significant in both normal physiology and in therapeutic contexts, such as in the treatment of certain cancers and in bone marrow recovery following chemotherapy. CSF2 is also involved in various inflammatory processes and has been studied for its potential role in autoimmune diseases. Its CAS number, 83869-56-1, is used for identification in chemical databases and regulatory contexts.

Colony-stimulatingfactor 2

83869-56-1: Colony-stimulating factor 2 (CSF2), also known as granulocyte-macrophage colony-stimulating factor (GM-CSF), is a glycoprotein that plays a crucial role in hematopoiesis, particularly in the differentiation and proliferation of myeloid progenitor cells into granulocytes and macrophages. It is produced by various cell types, including T cells, macrophages, and endothelial cells, in response to inflammatory stimuli. CSF2 functions by binding to its specific receptor, which activates signaling pathways that promote cell survival, proliferation, and differentiation. The substance is characterized by its ability to enhance the immune response, making it significant in both normal physiology and in therapeutic contexts, such as in the treatment of certain cancers and in bone marrow recovery following chemotherapy. CSF2 is also involved in various inflammatory processes and has been studied for its potential role in autoimmune diseases. Its CAS number, 83869-56-1, is used for identification in chemical databases and regulatory contexts.

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CAS 83869-56-1

Colony-stimulatingfactor 2

rec GM-CSF (murine)

Ref: 3D-FR110078