CAS 83873-16-9

(6α,9β,11β)-9,11-Epoxy-17-hydroxy-6-methylpregna-1,4-diene-3,20-dione

Description:

The chemical substance known as (6α,9β,11β)-9,11-Epoxy-17-hydroxy-6-methylpregna-1,4-diene-3,20-dione, with the CAS number 83873-16-9, is a synthetic steroid that exhibits anti-inflammatory and immunosuppressive properties. It is structurally related to natural corticosteroids, featuring a steroid backbone with specific functional groups that contribute to its biological activity. The presence of the epoxy group and hydroxyl group in its structure enhances its potency and specificity in interacting with glucocorticoid receptors. This compound is often studied for its potential therapeutic applications in treating conditions such as autoimmune diseases and allergies. Additionally, its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its efficacy and safety profile. As with many synthetic steroids, careful consideration of dosage and potential side effects is essential in clinical settings. Overall, this compound represents a significant interest in medicinal chemistry and pharmacology due to its unique structural characteristics and biological effects.

Formula: C₂₂H₂₈O₄

InChI: InChI=1S/C22H28O4/c1-12-9-17-15-6-8-21(25,13(2)23)20(15,4)11-18-22(17,26-18)19(3)7-5-14(24)10-16(12)19/h5,7,10,12,15,17-18,25H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22+/m0/s1

InChI key: InChIKey=SIYXFDGWCLUFNE-SJTSTTJWSA-N

SMILES: C[C@@]12[C@@]34[C@@](O3)(C[C@@]5(C)[C@]([C@@]4(C[C@H](C)C1=CC(=O)C=C2)[H])(CC[C@@]5(C(C)=O)O)[H])[H]

Synonyms:

• (6α,9β,11β)-9,11-Epoxy-17-hydroxy-6-methylpregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17-hydroxy-6-methyl-, (6α,9β,11β)-

Fluorometholone Impurity 10

CAS: 83873-16-9

Formula: C₂₂H₂₈O₄

Color and Shape: White To Off-White Solid

Molecular weight: 356.46

Ref: 4Z-F-643

Fluorometholone Epoxy Metradiene

CAS: 83873-16-9

Formula: C₂₂H₂₈O₄

Molecular weight: 356.46

Ref: ST-EA-CP-F31003

Epoxy Metradiene

Controlled Product

CAS: 83873-16-9

Applications Epoxy Metradiene is an impurity from synthesis of Fluorometholone (F593145),a glucocorticoid; anti-inflammatory.
References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982); Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984);

Formula: C₂₂H₂₈O₄

Color and Shape: Neat

Molecular weight: 356.46

Ref: TR-E589245

Epoxy metradiene

CAS: 83873-16-9

Please enquire for more information about Epoxy metradiene including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₂₈O₄

Purity: Min. 95%

Molecular weight: 356.5 g/mol

Ref: 3D-IDA87316