CAS 83881-09-8

Mometasone impurity D

CAS: 83881-09-8

Mometasone impurity D

Color and Shape: White To Off-White

Ref: 47-1283

Epoxy Mometasone Furoate ((9β, 11β, 16α)-21-Chloro-9,11-epoxy-17-[(2-furanylcarbonyl)oxy]-16-methylpregna-1,4-diene-3,20-dione)

CAS: 83881-09-8

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₇H₂₉ClO₆

Color and Shape: Yellow Pale Yellow Powder

Molecular weight: 484.16527

Ref: 45-1A07090

Mometasone Furoate EP Impurity D

CAS: 83881-09-8

Formula: C₂₇H₂₉ClO₆

Color and Shape: White To Off-White Solid

Molecular weight: 484.97

Ref: 4Z-M-145

21-Chloro-9,11β-epoxy-16α-methyl-3,20-dioxo-9β-pregna-1,4-dien-17-yl Furan-2-carboxylate

CAS: 83881-09-8

Color and Shape: White To Off-White

Ref: 86-MM1272.04

21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-d

CAS: 83881-09-8

Impurity Mometasone Furoate EP Impurity D
Applications A21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione (Mometasone EP Impurity D) is a impurity of Mometasone Furoate.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)

Formula: C₂₇H₂₉ClO₆

Color and Shape: White To Off-White

Molecular weight: 484.97

Ref: TR-C366525

21-Chloro-17α-[(2-furanylcarbonxyl-d3)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione

Controlled Product

CAS: 83881-09-8

Applications A deuterated impurity of Mometasone Furoate.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)

Formula: C₂₇H₂₆D₃ClO₆

Color and Shape: Neat

Molecular weight: 487.99

Ref: TR-C366527

21-Chloro-17α-[(2-furanylcarbonxyl-d3)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione

CAS: 83881-09-8

The interactive response of 21-chloro-17α-[(2-furanylcarbonxyl-d3)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione (CLD) and eosinophil cationic protein (ECP) is statistically significant. The combination of CLD and benzalkonium chloride (BZK) was more effective than BZK alone in reducing nasal symptoms in a population with allergic rhinitis. Furthermore, the combination of CLD and mometasone furoate (MF) is more effective than MF alone in reducing bronchoconstrictor response to methacholine in subjects with asthma. CLD and MF are not significantly different from each other. CLD is an agonist for the glucocorticoid receptor and has been shown to have antihistaminic effects at high concentrations in vitro.

Formula: C₂₇H₂₉ClO₆

Purity: Min. 95%

Molecular weight: 485 g/mol

Ref: 3D-IDA88109