CAS 83881-37-2

2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetamide

Description:

2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetamide, with the CAS number 83881-37-2, is a chemical compound that belongs to the class of piperazine derivatives. This substance typically exhibits properties such as being a white to off-white solid, with moderate solubility in organic solvents and limited solubility in water. Its molecular structure features a piperazine ring, which is known for its biological activity, particularly in pharmacology. The presence of the 4-chlorophenyl and phenyl groups suggests potential interactions with various biological targets, making it of interest in medicinal chemistry. The ethoxy and acetamide functional groups contribute to its overall polarity and may influence its pharmacokinetic properties, such as absorption and distribution. As with many compounds in this class, it may exhibit various biological activities, including potential effects on the central nervous system, but specific biological data would depend on empirical studies. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₂₁H₂₆ClN₃O₂

InChI: InChI=1/C21H26ClN3O2/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)25-12-10-24(11-13-25)14-15-27-16-20(23)26/h1-9,21H,10-16H2,(H2,23,26)

SMILES: c1ccc(cc1)C(c1ccc(cc1)Cl)N1CCN(CC1)CCOCC(=N)O

Synonyms:

• Acetamide, 2-[2-[4-[(4-Chlorophenyl)Phenylmethyl]-1-Piperazinyl]Ethoxy]-
• 2-(2-{4-[(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetamide
• Cetirizine Amide
• 2-[2-(4-[^a-(4-Chlorophenyl)benzyl]-1-piperazinyl)ethoxy]acetaMide, 97%
• 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetamide
• UCB-L 172

Cetirizine Related Compound C (2-(2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamide)

CAS: 83881-37-2

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₂₁H₂₆ClN₃O₂

Color and Shape: Powder

Molecular weight: 387.9

Ref: 45-1102952

Cetirizine USP Related Compound C

CAS: 83881-37-2

Formula: C₂₁H₂₆ClN₃O₂

Molecular weight: 387.17

Ref: 4Z-C-2076

Cetirizine amide

CAS: 83881-37-2

Cetirizine amide is an antihistamine that is used in the treatment of allergies. It is a racemic mixture of two enantiomers, cetirizine dihydrochloride and cetirizine monohydrochloride. Cetirizine amide is a chiral compound that can be prepared using preparative chiral high-performance liquid chromatography (chiralpak) with a chiral stationary phase.

Formula: C₂₁H₂₆ClN₃O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 387.9 g/mol

Ref: 3D-FC19909

Cetirizine Amide

Controlled Product

CAS: 83881-37-2

Applications Cetirizine impurity.
References Campoli-Richards, D.M., et al.: Drugs, 40, 762 (1990), Pandya, K.K., et al.: J. Pharm. Pharmacol., 48, 510 (1996), Zaater, M.F., et al.: J. Pharm. Biomed. Anal., 22, 739 (2000).

Formula: C₂₁H₂₆ClN₃O₂

Color and Shape: Neat

Molecular weight: 387.90

Ref: TR-C291080

Cetirizine USP Related Compound C

CAS: 83881-37-2

Formula: C₂₁H₂₆ClN₃O₂

Molecular weight: 387.90

Ref: ST-EA-CP-C14024