CAS 83883-10-7

Hydroxy-α-sanshool

Description:

Hydroxy-α-sanshool is a chemical compound primarily known for its presence in the Sichuan pepper, a spice that imparts a unique numbing and tingling sensation in the mouth. It belongs to the class of compounds known as sanshools, which are characterized by their long-chain aliphatic structures. Hydroxy-α-sanshool is recognized for its ability to activate specific sensory receptors, particularly those involved in the perception of pain and temperature, contributing to its distinctive sensory effects. The compound has garnered interest in both culinary and medicinal contexts due to its potential health benefits, including anti-inflammatory and analgesic properties. Its molecular structure includes hydroxyl groups, which enhance its solubility and reactivity. Hydroxy-α-sanshool is typically studied in the context of food chemistry and pharmacology, where its sensory and biological activities are explored. As with many natural compounds, its stability and efficacy can be influenced by factors such as temperature, pH, and the presence of other substances.

Formula: C₁₆H₂₅NO₂

InChI: InChI=1S/C16H25NO2/c1-4-5-6-7-8-9-10-11-12-13-15(18)17-14-16(2,3)19/h4-9,12-13,19H,10-11,14H2,1-3H3,(H,17,18)/b5-4+,7-6+,9-8-,13-12+

InChI key: InChIKey=LHFKHAVGGJJQFF-UEOYEZOQSA-N

SMILES: C(/C=C/CC/C=C\C=C\C=C\C)(NCC(C)(C)O)=O

Synonyms:

• 2,6,8,10-Dodecatetraenamide, N-(2-hydroxy-2-methylpropyl)-, (E,E,Z,E)-
• Hydroxy-α-sanshool
• 2E,6Z,8E,10E-Dodecatetraenoic acid N-(2-hydroxy-2-methylpropyl)amide
• (2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)-2,6,8,10-dodecatetraenamide
• 2,6,8,10-Dodecatetraenamide, N-(2-hydroxy-2-methylpropyl)-, (2E,6Z,8E,10E)-
• Hydroxy-alpha-Sanshool
• (2E,6Z,8E,10E)-N-(2-hydroxy-2-Methylpropyl)dodeca-2,6,8,10-tetra
• alpha-Hydroxy-Sanshool
• -N-(2-Hydroxy-2-methylpropyl)
• dodeca-2,6,8,10-tetraenamide
• （2E，6Z，8E，10E）-N-(2-hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide

(2E,6Z,8E,10E)-N-(2-Hydroxy-2-methylpropyl)dodeca-2,6,8,10-tetraenamide

CAS: 83883-10-7

Formula: C₁₆H₂₅NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 263.3752

Ref: IN-DA008HUA

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool

Purity: ≥95%

Molecular weight: 263.38g/mol

Ref: 54-BUP04863

Hydroxy-α-sanshool

CAS: 83883-10-7

Formula: C₁₆H₂₅NO₂

Purity: ≥ 98.0%

Color and Shape: White to beige solid

Molecular weight: 263.38

Ref: 7W-GY1523

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-alpha-sanshool exerts antiobesity and hypolipidemic activities in HFD rats by reducing liver oxidative stress and thus could be considered as a potential candidate drug to cure or prevent obesity and hyperlipidemia. It also has analgesic properties, it activates TRPV1 and TRPA1 in sensory neurons.

Formula: C₁₆H₂₅NO₂

Purity: 95%~99%

Molecular weight: 263.381

Ref: BP-BP4106

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent and TRPV1 non-covalent agonist (EC50s: 69 and 1.1 μM).

Formula: C₁₆H₂₅NO₂

Purity: 97.51% - 99.47%

Color and Shape: Solid

Molecular weight: 263.38

Ref: TM-T8307

Hydroxy-α-sanshool

CAS: 83883-10-7

Hydroxy-α-sanshool is a bioactive compound, which is a naturally occurring alkylamide. It is predominantly sourced from the fruit husks of the plant Zanthoxylum species, commonly known as Sichuan pepper. Hydroxy-α-sanshool is known for its unique mode of action, which involves the activation of specific ion channels in sensory neurons, notably the TRPV1 and TRPA1 channels. This activation results in a characteristic tingling and numbing sensation, commonly referred to as the "Sichuan pepper effect."

Formula: C₁₆H₂₅NO₂

Purity: Min. 98 Area-%

Color and Shape: Clear Viscous Liquid

Molecular weight: 263.38 g/mol

Ref: 3D-FH36486