CAS 83913-05-7

rel-3,4-Dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide

Description:

Rel-3,4-Dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide, with CAS number 83913-05-7, is a chemical compound that belongs to the class of substituted benzamides. It features a dichlorobenzene moiety, which contributes to its lipophilicity and potential biological activity. The presence of a pyrrolidine ring indicates that it may interact with various biological targets, possibly influencing neurotransmitter systems. This compound is characterized by its chiral centers, which can affect its pharmacological properties and interactions in biological systems. The specific stereochemistry (1R,2R) suggests that it may exhibit distinct activity compared to its enantiomers. Additionally, the dichloro substitution pattern can enhance its binding affinity to certain receptors or enzymes. While detailed toxicity and pharmacokinetic data may not be readily available, compounds of this nature are often studied for their potential therapeutic applications, particularly in the fields of neuroscience and pharmacology. As with any chemical substance, handling should be conducted with care, following appropriate safety protocols.

Formula: C₁₉H₂₆Cl₂N₂O

InChI: InChI=1/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18-/s2

InChI key: InChIKey=VQLPLYSROCPWFF-YTXKPMTANA-N

SMILES: N(C(CC1=CC(Cl)=C(Cl)C=C1)=O)(C)[C@H]2[C@@H](CCCC2)N3CCCC3

Synonyms:

• Benzeneacetamide, 3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]-, trans-
• Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, rel-
• rel-3,4-Dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide
• U 50488
• UM 1382

(+/-)-trans-U-50488 methanesulfonate

Controlled Product

CAS: 83913-05-7

(+/-)-trans-U-50488 Methanesulfonate is a potent, selective and competitive inhibitor of the calcium channel. It binds to the voltage sensor domain of voltage-gated calcium channels. This inhibition blocks the influx of calcium ions into the cell, thereby preventing depolarization and resulting in a decrease in neurotransmitter release. (+/-)-trans-U-50488 Methanesulfonate has been used as a research tool to study ion channels and protein interactions.

Formula: C₁₉H₂₆Cl₂N₂O•CH₄O₃S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 465.43 g/mol

Ref: 3D-XU181329