CAS 83915-83-7

Lisinopril dihydrate

Description:

Lisinopril dihydrate is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is a white to off-white crystalline powder that is soluble in water, which facilitates its absorption in the body. The chemical formula for lisinopril dihydrate reflects its dihydrate form, indicating the presence of two water molecules associated with each lisinopril molecule. This compound works by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. Lisinopril dihydrate is typically administered orally and is known for its long half-life, allowing for once-daily dosing. Common side effects may include dizziness, headache, and gastrointestinal disturbances, while serious adverse effects can involve renal impairment and hyperkalemia. As with any medication, it is essential to monitor patients for potential interactions with other drugs and underlying health conditions. Overall, lisinopril dihydrate is a widely used and effective medication in managing cardiovascular diseases.

Formula: C₂₁H₃₁N₃O₅·2H₂O

InChI: InChI=1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1

InChI key: InChIKey=CZRQXSDBMCMPNJ-ZUIPZQNBSA-N

SMILES: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)CCCCN)(=O)N2[C@H](C(O)=O)CCC2.O

Synonyms:

• N~2~-(1-carboxy-3-phenylpropyl)-L-lysyl-L-proline dihydrate
• N-[2-[4-[[[(Cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]5-methylpyrazinecarboxamide dihydrate
• N~2~-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline dihydrate
• L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, dihydrate
• Lisinopril dihydrate
• L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2)
• L-Proline, 1-[N2-(1-carboxy-3-phenylpropyl)-L-lysyl]-, dihydrate, (S)-

Lisinopril Dihydrate

CAS: 83915-83-7

Formula: C₂₁H₃₁O₅N₃·2H₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 441.53

Ref: 3B-L0220

Lisinopril Dihydrate

CAS: 83915-83-7

Color and Shape: Neat

Ref: 61-FOR0598.00

LISINOPRIL DIHYDRATE CRS

CAS: 83915-83-7

LISINOPRIL DIHYDRATE CRS

Formula: C₂₁H₃₅N₃O₇

Color and Shape: Powder

Molecular weight: 441.5185

Ref: 41-L0702000

Lisinopril dihydrate

CAS: 83915-83-7

Lisinopril dihydrate

Formula: C₂₁H₃₁N₃O₅

Purity: 91.5%

Color and Shape: White

Molecular weight: 405.22637

Ref: 47-695

LISINOPRIL FOR PEAK IDENTIFICATION CRS

CAS: 83915-83-7

LISINOPRIL FOR PEAK IDENTIFICATION CRS

Ref: 41-Y0001701

LISINOPRIL FOR SYSTEM SUITABILITY A CRS

CAS: 83915-83-7

LISINOPRIL FOR SYSTEM SUITABILITY A CRS

Color and Shape: Powder

Ref: 41-Y0001709

Lisinopril

CAS: 83915-83-7

Cardiovascular drugs, not elsewhere specified or includ

Formula: C₂₁H₃₁N₃O₅·2H₂O

Color and Shape: White Off-White Powder

Molecular weight: 405.22637

Ref: 45-1368609

Lisinopril dihydrate

CAS: 83915-83-7

Lisinopril dihydrate （MK-521) is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.

Formula: C₂₁H₃₅N₃O₇

Purity: 98.83% - 99.22%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 441.52

Ref: TM-T0706

L-Proline, N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-, hydrate (1:2)

CAS: 83915-83-7

Formula: C₂₁H₃₅N₃O₇

Purity: 99%

Color and Shape: Solid

Molecular weight: 441.5185

Ref: IN-DA003RAL

Lisinopril dihydrate, 10mM (in H2O)

CAS: 83915-83-7

Lisinopril dihydrate, 10mM (in H2O)

Purity: ≥98%

Molecular weight: 441.52g/mol

Ref: 54-BUP19973

Lisinopril dihydrate

CAS: 83915-83-7

Lisinopril dihydrate

Purity: ≥98%

Molecular weight: 441.52g/mol

Ref: 54-BUP18385

Lisinopril

CAS: 83915-83-7

Formula: C₂₁H₃₁O₅N₃·2H₂O

Purity: (Titration) 98.0 - 102.0 % (anhydrous basis)

Color and Shape: White to almost white crystalline powder

Molecular weight: 441.52

Ref: 7W-GP1712

Lisinopril dihydrate

Controlled Product

CAS: 83915-83-7

Formula: C₂₁H₃₁N₃O₅H₂O

Color and Shape: Neat

Molecular weight: 441.52

Ref: 04-C14640500

Lisinopril Dihydrate

Controlled Product

CAS: 83915-83-7

Formula: C₂₁H₃₁N₃O₅H₂O

Color and Shape: Neat

Molecular weight: 441.52

Ref: 86-MM0598.00

(S)-Lisinopril Dihydrate

CAS: 83915-83-7

Stability Hygroscopic
Applications An orally active angiotensin-converting enzyme (ACE) inhibitor. S,S,S-Isomer of Lisinopril.
References Goa, K.L., et al.: Drugs, 52, 564 (1996), Chaturvedi, N., et al.: Lancet, 351, 28 (1998)

Formula: C₂₁H₃₁N₃O₅·2H₂O

Color and Shape: White

Molecular weight: 441.52

Ref: TR-L468985

LISINOPRIL DIHYDRATE

CAS: 83915-83-7

Purity: 99%

Molecular weight: 441.5249939

Ref: 10-F817920

2-Deoxy-3,4,6-tri-O-pivaloyl-D-glucopyranosyl azide

CAS: 83915-83-7

2-Deoxy-3,4,6-tri-O-pivaloyl-D-glucopyranosyl azide is a drug that regulates the blood pressure. It is an oral hypoglycaemic agent that has been shown to lower blood sugar levels in patients with type 2 diabetes mellitus. The drug is metabolized in the liver by cytochrome p450 enzymes and can cause interactions with drugs such as lisinopril, which are metabolized by these enzymes. 2DGPA has been shown to be effective at lowering blood pressure in a low-dose group of patients with essential hypertension. The signal peptide sequence was detected in the protein sequencing of a biological sample from rats treated with 2DGPA. This drug also reduces natriuretic peptide levels and has a rate constant of 4s−1M−1s−1.

Formula: C₂₁H₃₅N₃O₇

Purity: Min. 95%

Molecular weight: 441.53 g/mol

Ref: 3D-MD08483