CAS 83918-61-0

5′-Thymidylic acid, mono(4-nitrophenyl) ester, monoammonium salt

Description:

5′-Thymidylic acid, mono(4-nitrophenyl) ester, monoammonium salt, with the CAS number 83918-61-0, is a chemical compound derived from thymidine, a nucleoside component of DNA. This compound features a thymidine backbone esterified at the 5′ position with a 4-nitrophenyl group, which imparts specific reactivity and properties. The presence of the ammonium salt form suggests that it can exist in a protonated state, enhancing its solubility in polar solvents. The 4-nitrophenyl moiety is known for its electron-withdrawing characteristics, which can influence the compound's reactivity in biochemical applications, such as in enzyme assays or as a substrate in nucleic acid synthesis. Additionally, the compound may exhibit biological activity due to its structural similarity to nucleotides, potentially interacting with nucleic acid processes. Overall, this compound is of interest in biochemical research and synthetic applications, particularly in the fields of molecular biology and medicinal chemistry.

Formula: C₁₆H₁₈N₃O₁₀P·H₃N

InChI: InChI=1S/C16H18N3O10P.H3N/c1-9-7-18(16(22)17-15(9)21)14-6-12(20)13(28-14)8-27-30(25,26)29-11-4-2-10(3-5-11)19(23)24;/h2-5,7,12-14,20H,6,8H2,1H3,(H,25,26)(H,17,21,22);1H3/t12-,13+,14+;/m0./s1

InChI key: InChIKey=UHFBCZJBOZBWER-SOIKFHLCSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(OC3=CC=C(N(=O)=O)C=C3)(=O)O)[C@@H](O)C2)C=C(C)C(=O)N1.N

Synonyms:

• 5′-Thymidylic acid, mono(4-nitrophenyl) ester, monoammonium salt
• Thymidine 5-phosphoric acid-4-nitrophenylester ammonium salt

4-Nitrophenyl Thymidine-5′-monophosphate, Ammonium Salt

Controlled Product

CAS: 83918-61-0

Applications 4-Nitrophenyl Thymidine-5′-monophosphate, Ammonium Salt is a chromogenic substrate for Phosphodiesterase l, which is a marker enzyme for plasma membranes.
References W.E. Razzell, H.G. Khorana, J. Biol. Chem. 1959, 234, 2105; W.E. Razzell, Experientia 1967, 23, 321; B. Storrie, E.A. Madden, Meth. Enzymol. 1990, 182, 203; P.J. Edelson, C. Erbs, J. Exp. Med. 1978, 147, 77; P.S. Morahan et al., J. Immunol. 1980, 125, 131;

Formula: C₁₆H₁₈N₃O₁₀P•NH₃

Color and Shape: Neat

Molecular weight: 443.30 + (17.03)

Ref: TR-N545115

4-Nitrophenyl thymidine-5'-monophosphate, ammonium salt

CAS: 83918-61-0

4-Nitrophenyl thymidine-5'-monophosphate, ammonium salt is a chemical compound that belongs to the group of versatile building blocks. It is a fine chemical, which has been used as a reagent and speciality chemical in research. 4-Nitrophenyl thymidine-5'-monophosphate, ammonium salt can be used as an intermediate in the synthesis of complex compounds. This compound is also useful as a scaffold for reactions with other organic molecules.

Formula: C₁₆H₂₁N₄O₁₀P

Purity: Min. 95.0 Area-%

Molecular weight: 460.34 g/mol

Ref: 3D-N-5185