CAS 83919-23-7
:Mometasone furoate
Description:
Mometasone furoate is a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. It is primarily used in the treatment of various inflammatory skin conditions, allergic rhinitis, and asthma. The compound exhibits a high affinity for glucocorticoid receptors, which enhances its efficacy in reducing inflammation and immune responses. Mometasone furoate is characterized by its low systemic bioavailability when administered topically, minimizing potential side effects associated with systemic corticosteroids. It is typically formulated as a cream, ointment, or nasal spray, allowing for targeted delivery to affected areas. The substance is known for its stability and solubility in organic solvents, which facilitates its incorporation into various pharmaceutical formulations. Additionally, it has a favorable safety profile, making it suitable for both short-term and long-term use in appropriate dosages. As with all corticosteroids, careful consideration of dosage and duration of treatment is essential to mitigate potential side effects, such as skin thinning or adrenal suppression, particularly with prolonged use.
Formula:C32H32Cl2O8
InChI:InChI=1/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18?,19?,21+,24+,25+,26+,27+/m1/s1
InChI key:InChIKey=WOFMFGQZHJDGCX-ZULDAHANSA-N
SMILES:O(C(=O)C1=CC=CO1)[C@@]2(C(CCl)=O)[C@]3(C)[C@@](C[C@H]2C)([C@]4([C@](Cl)([C@@H](O)C3)[C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H]
Synonyms:- (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8Xi,11Beta,14Xi,16Alpha)-9,21-Dichloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Furan-2-Carboxylate
- 9-Chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one furoate
- Asmanex
- Asmanex Twisthaler
- Ecural
- Elocom
- Elocon
- Elomet
- Mometasone 17-(2-furoate)
- Mometasone 17-Furoate
- Monovo
- Nasonex
- Ovixan
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-, (11β,16α)-
- Sch 32088
- Twisthaler
- Mometasone furoate
- Sch-32088, Elocon, Nasonex
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-, (11b,16a)-(9CI)
- (11BETA,16ALPHA)-9,21-DICHLORO-17-[(2-FURANYLCARBONYL)OXY]-11-HYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE
- Pregna-1,4-Diene-3,20-Dione,9,21-Dichloro-17-[(2-Furanylcarbonyl)Oxy]-11-Hydroxy-16-Methyl-,(11Beta,16Alpha)-
- srh-32088
- MOMETASONE FUAROATE
- (+)-9,21-Dichloro-11',17'-dihydroxy-16-alpha-methyl-1,4-pregnadiene-3,20-dione-17-(2-furoate)
- (11-beta,16-alpha)-xy-16-methyl
- 9，21-Dichloro-11β，17-hydrox-16α-methylpregm-1，4-diene-3，20-dione 17-(2-furoate)
- MOMETOSONE FUROATE MONOHYDRATE
- pregna-1,4-diene-3,20-dione,9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydro
- See more synonyms
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Found 23 products.
Mometasone Furoate
CAS:Formula:C27H30Cl2O6Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:521.43Mometasone furoate
CAS:Mometasone furoateFormula:C27H30Cl2O6Purity:99.3%Color and Shape:White To Off-WhiteMolecular weight:520.14194MOMETASONE FUROATE CRS
CAS:MOMETASONE FUROATE CRSFormula:C27H30Cl2O6Color and Shape:AddedMolecular weight:521.4295Mometasone Furoate
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C27H30Cl2O6Color and Shape:White Off-White PowderMolecular weight:520.14194(11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
CAS:Formula:C27H30Cl2O6Purity:98%Color and Shape:SolidMolecular weight:521.4295Mometasone furoate
CAS:Mometasone furoate (Sch32088) is a pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA andFormula:C27H30Cl2O6Purity:99.43% - 99.48%Color and Shape:SolidMolecular weight:521.43Mometasone Furoate Impurity 4
CAS:Formula:C27H28Cl2O6Color and Shape:White To Off-White SolidMolecular weight:519.42Mometasone Furoate-d3
CAS:Formula:C27H27D3Cl2O6Color and Shape:White To Off-White SolidMolecular weight:524.45Mometasone furoate
CAS:Formula:C27H30Cl2O6Purity:≥ 98.0% (dried basis)Color and Shape:White to off-white powderMolecular weight:521.43Mometasone Furoate
CAS:Formula:C27H30Cl2O6Color and Shape:White To Off-White SolidMolecular weight:521.43Mometasone Furoate
CAS:Controlled ProductFormula:C27H30Cl2O6Color and Shape:NeatMolecular weight:521.43Mometasone Furoate-d3
CAS:Controlled ProductApplications A deuterated topical corticosteroid used as an anti-inflammatory.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)Formula:C27H27D3Cl2O6Color and Shape:NeatMolecular weight:524.45Mometasone Furoate
CAS:Applications Mometasone Furoate is a topical corticosteroid used as an anti-inflammatory.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)Formula:C27H30Cl2O6Color and Shape:NeatMolecular weight:521.43Mometasone Furoate-d8
CAS:Controlled ProductApplications Mometasone Furoate-d8 is the isotope labelled analog of Mometasone Furoate (M490000); a topical corticosteroid used as an anti-inflammatory.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987); Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)Formula:C27D8H22Cl2O6Color and Shape:NeatMolecular weight:529.479
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