CAS 839707-55-0

Benzamide, N-[3-[1,4-dihydro-1-methyl-7-[(1-methyl-1H-pyrazol-3-yl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)-

Description:

Benzamide, N-[3-[1,4-dihydro-1-methyl-7-[(1-methyl-1H-pyrazol-3-yl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)-, with CAS number 839707-55-0, is a complex organic compound characterized by its unique structural features. It contains a benzamide moiety, which is known for its applications in pharmaceuticals and as a building block in organic synthesis. The presence of a trifluoromethyl group enhances its lipophilicity and may influence its biological activity. The compound also features a pyrimidine derivative, which is often associated with various biological activities, including anti-cancer and anti-inflammatory properties. The incorporation of a pyrazole ring suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its molecular structure indicates potential for diverse reactivity and applications in drug development. As with many complex organic compounds, its solubility, stability, and reactivity would depend on the specific conditions under which it is handled.

Formula: C₂₆H₂₃F₃N₈O₂

Synonyms:

• Benzamide, N-[3-[1,4-dihydro-1-methyl-7-[(1-methyl-1H-pyrazol-3-yl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)-

SIJ1777

CAS: 839707-55-0

SIJ1777, a derivative of GNF-7, exhibits potent anticancer effects against melanoma cells harboring BRAFI/II/III mutations. The compound significantly inhibits the activation of MEK, ERK, and AKT. Furthermore, SIJ1777 notably induces apoptosis (cell death) and effectively prevents migration, invasion, and anchorage-independent growth of melanoma cells with BRAFI/II/III mutations.

Formula: C₂₆H₂₃F₃N₈O₂

Color and Shape: Solid

Molecular weight: 536.51

Ref: TM-T200137