CAS 839712-15-1

N-Desmethyl Cariprazine

CAS: 839712-15-1

Formula: C₂₀H₃₀Cl₂N₄O

Molecular weight: 413.39

Ref: 4Z-C-145003

N-Desmethyl Cariprazine

CAS: 839712-15-1

Formula: C₂₀H₃₀Cl₂N₄O

Molecular weight: 413.38

Ref: ST-EA-CP-C57004

Desmethyl Cariprazine

CAS: 839712-15-1

Applications Desmethyl Cariprazine, is a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
References Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)

Formula: C₂₀H₃₀Cl₂N₄O

Color and Shape: Neat

Molecular weight: 413.38

Ref: TR-D291368

Desmethyl cariprazine

CAS: 839712-15-1

Desmethyl cariprazine is a potent and selective inhibitor of the enzyme catechol-O-methyltransferase, which is responsible for the breakdown of dopamine. It has been shown to have antipsychotic effects in animal models. Desmethyl cariprazine is also a research tool for investigating protein interactions and receptor activation.

Formula: C₂₀H₃₀Cl₂N₄O

Purity: Min. 95%

Molecular weight: 413.4 g/mol

Ref: 3D-PIB71215

Desmethyl cariprazine

CAS: 839712-15-1

Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).

Formula: C₂₀H₃₀Cl₂N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 413.38

Ref: TM-T15100