CAS 84-04-8

Pipamazine

Description:

Pipamazine is a chemical compound classified as an antipsychotic medication, primarily used in the treatment of various psychiatric disorders. It belongs to the class of phenothiazines and exhibits properties that can help manage symptoms of schizophrenia and other mental health conditions. The molecular structure of pipamazine includes a piperazine ring, which contributes to its pharmacological activity. It functions primarily as a dopamine antagonist, influencing neurotransmitter pathways in the brain. Pipamazine is known for its sedative effects and may also have antiemetic properties, making it useful in managing nausea and vomiting associated with certain treatments. The compound is typically administered in oral form, and its dosage can vary based on the specific condition being treated and the patient's response. As with many medications, pipamazine may have side effects, including sedation, weight gain, and potential extrapyramidal symptoms, necessitating careful monitoring by healthcare professionals. Overall, pipamazine plays a significant role in psychiatric therapy, although its use must be balanced with considerations of efficacy and safety.

Formula: C₂₁H₂₄ClN₃OS

InChI: InChI=1S/C21H24ClN3OS/c22-16-6-7-20-18(14-16)25(17-4-1-2-5-19(17)27-20)11-3-10-24-12-8-15(9-13-24)21(23)26/h1-2,4-7,14-15H,3,8-13H2,(H2,23,26)

InChI key: InChIKey=OSJJYEUEJRVVOD-UHFFFAOYSA-N

SMILES: C(CCN1CCC(C(N)=O)CC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3

Synonyms:

• 1-(3-(2-Chlorophenothiazin-10-Yl)Propyl)Piperidine-4-Carboxamide
• 1-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-4-piperidinecarboxamide
• 1-[3-(2-Chlorophenothiazin-10-yl)propyl]isonipecotamide
• 1-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperidine-4-carboxamide
• 10-[3-(4-Carbamoylpiperidino)propyl]-2-chlorophenothiazine
• 4-Piperidinecarboxamide, 1-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-
• Isonipecotamide, 1-[3-(2-chlorophenothiazin-10-yl)propyl]-
• Mornidine
• Nausidol
• Nometine
• Rp 9153

Pipamazine

CAS: 84-04-8

Color and Shape: Neat

Ref: 61-FOR1603.00

Pipamazine

CAS: 84-04-8

Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.
References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);

Formula: C₂₁H₂₄ClN₃OS

Color and Shape: Neat

Molecular weight: 401.95

Ref: TR-P475190