CAS 84-31-1

(8α)-6′-Methoxycinchonan-9-one

Description:

(8α)-6′-Methoxycinchonan-9-one, with the CAS number 84-31-1, is a chemical compound that belongs to the class of cinchona alkaloids, which are derived from the bark of the cinchona tree. This compound is characterized by its unique bicyclic structure, which includes a quinoline moiety and a methoxy group at the 6' position. It typically exhibits a chiral center, contributing to its stereochemistry and potential biological activity. The presence of the methoxy group can influence its solubility and reactivity, making it of interest in medicinal chemistry, particularly for its potential antimalarial and analgesic properties. The compound may also participate in various chemical reactions, such as alkylation or oxidation, due to the functional groups present. Its specific properties, such as melting point, boiling point, and solubility, can vary based on the purity and form of the compound. Overall, (8α)-6′-Methoxycinchonan-9-one is a notable compound in the study of natural products and their derivatives.

Formula: C₂₀H₂₂N₂O₂

InChI: InChI=1S/C20H22N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19H,1,7,9-10,12H2,2H3/t13-,14-,19-/m0/s1

InChI key: InChIKey=SRFCUPVBYYAMIL-NJSLBKSFSA-N

SMILES: C(=O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@H]3[N@@]4C[C@H](C=C)[C@](C3)(CC4)[H]

Synonyms:

• (8alpha)-6'-Methoxycinchonan-9-one
• (8α)-6′-Methoxycinchonan-9-one
• 6'-Methoxycinchonan-9-One
• Cinchonan-9-one, 6'-methoxy-, (8alpha)-
• Cinchonan-9-one, 6′-methoxy-, (8α)-
• Icq 15
• Nsc 15307
• Quininone

Quininone (Cinchonan-9-one, 6'-methoxy-, (8α)-)

CAS: 84-31-1

Alkaloids of cinchona (excluding quinine and its salts) and their derivatives; salts thereof

Formula: C₂₀H₂₂N₂O₂

Color and Shape: Yellow Beige Powder

Molecular weight: 322.16813

Ref: 45-1597504

(8α)-6′-Methoxycinchonan-9-one

CAS: 84-31-1

Formula: C₂₀H₂₂N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 322.4009

Ref: IN-DA00G4QO

2'-Quinidinone (Mixture of Diastereomers)

CAS: 14528-53-1, 84-31-1

Formula: C₂₀H₂₂N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 322.41

Ref: 4Z-Q-046

Quininone

CAS: 84-31-1

Formula: C₂₀H₂₄N₂O₂

Color and Shape: Pale Yellow Solid

Molecular weight: 324.42

Ref: 4Z-Q-0412

Quininone

CAS: 84-31-1

Applications Quininone has been shown to have antimalarial activity in mice. Quininone has been shown to aid the binding of drug-induced antibodies to human platelets.
References Klayman, D.L., et. al.: J. Med. Chem., 16, 1042 (1973); Christie, D.J., et. al.: J. Lab. Clin. Med., 104, 730 (1984)

Formula: C₂₀H₂₂N₂O₂

Color and Shape: White To Light Beige

Molecular weight: 322.40

Ref: TR-Q694400

Quininone

CAS: 84-31-1

Quininone is a chemical compound that contains an aromatic ring and a quinone group, which is composed of two nitrogens and one oxygen. It can be synthesized by the intramolecular addition of hydrochloric acid to calcium stearate in the presence of phosphorus pentachloride. Quininone has been shown to have anticancer activity and is being studied for its potential use as a pharmaceutical agent. The anticancer activity of quininones may be due to their ability to inhibit DNA synthesis, RNA synthesis, protein synthesis, or other cellular processes.

Formula: C₂₀H₂₂N₂O₂

Purity: Min. 95%

Molecular weight: 322.4 g/mol

Ref: 3D-AAA08431

Quininone

CAS: 84-31-1

Formula: C₂₀H₂₂N₂O₂

Molecular weight: 322.41

Ref: ST-EA-CP-Q9005