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CAS 84057-84-1

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Lamotrigine

Description:
Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder. It functions by stabilizing neuronal membranes and inhibiting the release of excitatory neurotransmitters, thereby reducing the frequency of seizures and mood episodes. Chemically, lamotrigine is classified as a phenyltriazine derivative, with a molecular formula that reflects its complex structure. It is typically administered in tablet form and is known for its relatively favorable side effect profile compared to other anticonvulsants. Lamotrigine exhibits good oral bioavailability and is metabolized primarily in the liver, with its elimination half-life varying based on concomitant medications. The drug is also notable for its potential to cause skin rashes, some of which can be serious, necessitating careful monitoring during treatment. Overall, lamotrigine is a critical therapeutic agent in the management of epilepsy and mood disorders, with ongoing research exploring its broader applications in neurology and psychiatry.
Formula:C9H7Cl2N5
InChI:InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChI key:InChIKey=PYZRQGJRPPTADH-UHFFFAOYSA-N
SMILES:NC=1C(=NN=C(N)N1)C2=C(Cl)C(Cl)=CC=C2
Synonyms:
  • 1,2,4-Triazine-3,5-diamine, 6-(2,3-dichlorophenyl)-
  • 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
  • 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine
  • 6-(2,3-Dichlorophenyl)-1,2,4-Triazine-3,5-Diamine
  • Bw 430C
  • Epilepax
  • LTG
  • Lamictal
  • Lamictal XR
  • Lamidus
  • See more synonyms
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