CAS 84057-84-1

Lamotrigine

Description:

Lamotrigine is an anticonvulsant medication primarily used to treat epilepsy and bipolar disorder. It functions by stabilizing neuronal membranes and inhibiting the release of excitatory neurotransmitters, thereby reducing the frequency of seizures and mood episodes. Chemically, lamotrigine is classified as a phenyltriazine derivative, with a molecular formula that reflects its complex structure. It is typically administered in tablet form and is known for its relatively favorable side effect profile compared to other anticonvulsants. Lamotrigine exhibits good oral bioavailability and is metabolized primarily in the liver, with its elimination half-life varying based on concomitant medications. The drug is also notable for its potential to cause skin rashes, some of which can be serious, necessitating careful monitoring during treatment. Overall, lamotrigine is a critical therapeutic agent in the management of epilepsy and mood disorders, with ongoing research exploring its broader applications in neurology and psychiatry.

Formula: C₉H₇Cl₂N₅

InChI: InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)

InChI key: InChIKey=PYZRQGJRPPTADH-UHFFFAOYSA-N

SMILES: NC=1C(=NN=C(N)N1)C2=C(Cl)C(Cl)=CC=C2

Synonyms:

• 1,2,4-Triazine-3,5-diamine, 6-(2,3-dichlorophenyl)-
• 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
• 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine
• 6-(2,3-Dichlorophenyl)-1,2,4-Triazine-3,5-Diamine
• Bw 430C
• Epilepax
• LTG
• Lamictal
• Lamictal XR
• Lamidus
• Lamitrin
• Lamotrigin
• Lamotrigina
• Lamtox

Lamotrigine

Controlled Product

CAS: 84057-84-1

Formula: C₉H₇Cl₂N₅

Color and Shape: Neat

Molecular weight: 256.09

Ref: 04-C14591900

Lamotrigine

CAS: 84057-84-1

Formula: C₉H₇CI₂N₅

Molecular weight: 256.09

Ref: ST-EA-CP-L10000

Lamotrigine

Controlled Product

CAS: 84057-84-1

Applications An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),

Formula: C₉H₇Cl₂N₅

Color and Shape: Neat

Molecular weight: 256.09

Ref: TR-L173250

Lamotrigine - Bio-X ™

Controlled Product

CAS: 84057-84-1

Lamotrigine is an antiepileptic phenyltriazine drug that is used to treat epilepsy and as a mood stabilizer in bipolar disorder. Although, this drug’s action is not fully well understood it is similar to carbamazepine which involves inhibiting voltage-sensitive sodium channels. Lamotrigine blocks voltage-sensitive sodium channels, which reduces neuronal excitability by blocking action potentials.

Formula: C₉H₇Cl₂N₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 256.09 g/mol

Ref: 3D-BL166799

Lamotrigine

Controlled Product

CAS: 84057-84-1

Sodium channel blocker; antileptic

Formula: C₉H₇Cl₂N₅

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 256.09 g/mol

Ref: 3D-ID58057

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

CAS: 84057-84-1

Formula: C₉H₇Cl₂N₅

Purity: 95%

Color and Shape: Solid, White to very pale yellow powder

Molecular weight: 256.09

Ref: 10-F093440

Lamotrigine

CAS: 84057-84-1

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine

Formula: C₉H₇Cl₂N₅

Purity: 98%

Molecular weight: 256.09

Ref: IN-DG22808