CAS 84057-95-4

Ropivacaine

Description:

Ropivacaine is a local anesthetic belonging to the amide class, primarily used for regional anesthesia and pain management. It is characterized by its ability to block nerve conduction by inhibiting sodium ion influx through voltage-gated sodium channels, leading to a reversible loss of sensation in targeted areas. Ropivacaine is known for its relatively lower cardiotoxicity compared to other local anesthetics, making it a preferred choice in certain clinical settings. The substance is typically administered via injection and is available in various concentrations. Its pharmacokinetic profile includes a slower onset and longer duration of action, which can be advantageous for prolonged analgesia. Ropivacaine is also noted for its lower potential for systemic toxicity, allowing for safer use in epidural and peripheral nerve blocks. Additionally, it has a chiral center, existing as a single enantiomer, which contributes to its efficacy and safety profile. Overall, Ropivacaine is a valuable agent in the field of anesthesiology and pain management.

Formula: C₁₇H₂₆N₂O

InChI: InChI=1/C17H26N2O.CH4O3S/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;1-5(2,3)4/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H3,(H,2,3,4)

InChI key: InChIKey=ZKMNUMMKYBVTFN-HNNXBMFYSA-N

SMILES: C(NC1=C(C)C=CC=C1C)(=O)[C@H]2N(CCC)CCCC2

Synonyms:

• (-)-Lea 103
• (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
• (2S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide
• (S)-(-)-1-propyl-2\',6\'-pipecolinoxylidide
• (S)-(-)-Ropivacaine
• 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (2S)-
• 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, (S)-
• Anapeine
• N-(2,6-Dimethylphenyl)-1-propyl-piperidine-2-carboxamide
• N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide methanesulfonate (1:1)
• Narop
• Naropeine
• Naropine
• Ropivacaine
• (S)-N-(2，6-Dimethylphenyl)-1-pKIpyl-2-piperidinecarboxamide
• ROPIVACAINE MESYLATER
• (2S)-1-Propyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
• Naropin
• (2S)-1-Propyl-2-(2,6-dimethylphenyl)carbamoylpiperidine
• ROPACARAINEHCL

Ropivacaine

CAS: 84057-95-4

Formula: C₁₇H₂₆N₂O

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 274.41

Ref: 3B-R0251

Ropivacaine

CAS: 84057-95-4

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₂₆N₂O

Color and Shape: White Off-White Powder

Molecular weight: 274.20451

Ref: 45-1605497

Ropivacaine

CAS: 84057-95-4

Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.

Formula: C₁₇H₂₆N₂O

Purity: 97.75% - >99.99%

Color and Shape: Solid

Molecular weight: 274.40

Ref: TM-T0386L

Ropivacaine

CAS: 84057-95-4

Ropivacaine

Purity: 98%

Molecular weight: 274.4g/mol

Ref: 54-OR1030385

Ropivacaine

CAS: 84057-95-4

Ropivacaine

Purity: ≥95%

Molecular weight: 274.4g/mol

Ref: 54-BUP10995

Ropivacaine

CAS: 84057-95-4

Formula: C₁₇H₂₆N₂O

Color and Shape: Off-White Solid

Molecular weight: 274.41

Ref: 4Z-R-222

Ropivacaine

CAS: 84057-95-4

Formula: C₁₇H₂₆N₂O

Molecular weight: 274.40

Ref: 7W-GP7588

(S)-Ropivacaine

Controlled Product

CAS: 84057-95-4

Applications (S)-Ropivacaine acts as a local anaesthetic for use during medical procedures. Frequently used in epidural procedures as a labor analgesia
References Bataille, A. et al.: Brit. J. Anaesthesia., 112, 703 (2014); Zhai, Y. et al.: Int. j. Pharm., 47, 103 (2014); Yue, H. et al.: Chin Med. J., 126. 4301 (2013);

Formula: C₁₇H₂₆N₂O

Color and Shape: Neat

Molecular weight: 274.40

Ref: TR-R674995

Ropivacaine

Controlled Product

CAS: 84057-95-4

Ropivacaine is an amide local anesthetic that is used to provide pain relief during surgery. It can also be used in other medical procedures, such as endoscopy and diagnostic angiography. Ropivacaine binds to the α1-acid glycoprotein in the blood, which prevents its passage into the central nervous system. Ropivacaine has been shown to have a polymerase chain-reaction (PCR) assay of clinical properties and a matrix effect on bupivacaine. Injection solutions containing ropivacaine are available with concentrations between 0.5% and 2%. The optimum concentration depends on the type of procedure being performed and the desired duration of anesthesia. Ropivacaine has also been shown to have cardiac effects, including an increase in heart rate, but does not appear to interfere with cardiac conduction or contractility. It also provides analgesia by blocking nerve impulses from reaching the brain.

Formula: C₁₇H₂₆N₂O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 274.4 g/mol

Ref: 3D-FR178417