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CAS 842133-18-0

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Canagliflozin

Description:
Canagliflozin is a medication primarily used in the management of type 2 diabetes mellitus. It belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, which function by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The chemical formula for Canagliflozin is C21H25ClO5S, and it features a sulfonyl group, a chlorobenzene moiety, and a glucose-like structure, which contribute to its pharmacological activity. Canagliflozin is typically administered orally and is known for its potential benefits beyond glycemic control, including weight loss and cardiovascular protection. Common side effects may include urinary tract infections and dehydration. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Canagliflozin.
Formula:C24H25FO5S
InChI:InChI=1S/C24H25FO5S/c1-13-2-3-15(24-23(29)22(28)21(27)19(12-26)30-24)10-16(13)11-18-8-9-20(31-18)14-4-6-17(25)7-5-14/h2-10,19,21-24,26-29H,11-12H2,1H3/t19-,21-,22+,23-,24+/m1/s1
InChI key:InChIKey=XTNGUQKDFGDXSJ-ZXGKGEBGSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2
Synonyms:
  • (1S)-1,5-Anhydro-1-C-(3-((5-(4-Fluorophenyl)-2-Thienyl)Methyl)-4-Methylphenyl)-D-Glucitol
  • (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-<span class="text-smallcaps">D</span>-glucitol
  • 1-(β-<span class="text-smallcaps">D</span>-Glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene
  • 1-(β-D-glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienyl-methyl) benzene
  • <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-
  • Canaglifozin
  • Invokana
  • Jnj 24831754Zae
  • Jnj 28431754
  • Jnj 28431754Aaa
  • See more synonyms
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