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CAS 84377-97-9

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Nitromazenil

Description:
Nitromazenil, with the CAS number 84377-97-9, is a chemical compound that belongs to the class of nitro derivatives of benzodiazepines. It is primarily recognized for its role as a selective antagonist of the benzodiazepine receptor, which makes it significant in pharmacological research, particularly in the study of anxiety and sedation mechanisms. The compound exhibits a high affinity for the central nervous system, influencing GABAergic neurotransmission. Nitromazenil is characterized by its nitro group, which contributes to its unique chemical properties and biological activity. In laboratory settings, it is often utilized to investigate the effects of benzodiazepines and to explore potential therapeutic applications in treating benzodiazepine overdose or dependence. Safety and handling precautions are essential due to its pharmacological effects, and it is typically handled in controlled environments. As with many chemical substances, further research is ongoing to fully elucidate its mechanisms and potential applications in medicine.
Formula:C15H14N4O5
Synonyms:
  • 5,6-Dihydro-5-methyl-8-nitro-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine-3-carboxylic acid ethyl ester
  • Ro 15-2344
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