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CAS 84418-43-9

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9-fluorenylmethyl carbamate

Description:
9-Fluorenylmethyl carbamate, with the CAS number 84418-43-9, is a chemical compound commonly used as a protecting group for amines in organic synthesis. It features a fluorenylmethyl group attached to a carbamate functional group, which enhances its stability and reactivity. This compound is typically a white to off-white solid, and it is soluble in organic solvents such as dichloromethane and methanol, but generally insoluble in water. The presence of the fluorenyl moiety provides steric hindrance, making it an effective protecting group that can be selectively removed under mild conditions, often using nucleophiles or specific reagents. Its application is particularly valuable in the synthesis of complex organic molecules, including pharmaceuticals and natural products, where the protection and subsequent deprotection of amines are crucial steps. Additionally, 9-fluorenylmethyl carbamate is characterized by its stability under a variety of reaction conditions, making it a reliable choice for chemists in synthetic pathways.
Formula:C15H13NO2
InChI:InChI=1/C15H13NO2/c16-15(17)18-9-14-12-7-3-1-5-10(12)11-6-2-4-8-13(11)14/h1-8,14H,9H2,(H2,16,17)
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N)O
Synonyms:
  • Fmoc-NH2
  • 9H-fluoren-9-ylmethyl carbamate
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